BRASILI, Livio
 Distribuzione geografica
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Continente #
NA - Nord America 17.171
EU - Europa 10.154
AS - Asia 8.446
SA - Sud America 1.229
AF - Africa 162
OC - Oceania 42
Continente sconosciuto - Info sul continente non disponibili 9
Totale 37.213
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Nazione #
US - Stati Uniti d'America 16.866
GB - Regno Unito 2.884
CN - Cina 2.479
SG - Singapore 2.315
DE - Germania 1.538
IT - Italia 1.503
SE - Svezia 1.342
HK - Hong Kong 1.064
BR - Brasile 950
VN - Vietnam 938
FI - Finlandia 724
RU - Federazione Russa 483
UA - Ucraina 435
FR - Francia 365
TR - Turchia 289
IN - India 273
KR - Corea 262
BD - Bangladesh 239
BG - Bulgaria 181
CA - Canada 173
BE - Belgio 162
NL - Olanda 126
IE - Irlanda 93
AR - Argentina 84
ID - Indonesia 75
IQ - Iraq 72
MX - Messico 71
PL - Polonia 67
JP - Giappone 65
RO - Romania 62
EC - Ecuador 49
PK - Pakistan 46
CO - Colombia 40
ES - Italia 40
IR - Iran 40
LT - Lituania 40
IL - Israele 33
ZA - Sudafrica 33
CL - Cile 31
VE - Venezuela 31
AE - Emirati Arabi Uniti 30
PH - Filippine 29
KE - Kenya 24
NZ - Nuova Zelanda 24
SA - Arabia Saudita 23
MA - Marocco 22
EG - Egitto 21
OM - Oman 17
PY - Paraguay 17
AU - Australia 16
CH - Svizzera 16
TH - Thailandia 16
UZ - Uzbekistan 16
AT - Austria 15
BY - Bielorussia 14
JO - Giordania 14
MY - Malesia 14
KZ - Kazakistan 13
TN - Tunisia 13
TW - Taiwan 12
AZ - Azerbaigian 11
DZ - Algeria 11
NP - Nepal 11
CR - Costa Rica 10
CZ - Repubblica Ceca 10
CI - Costa d'Avorio 9
PT - Portogallo 9
UY - Uruguay 9
AL - Albania 8
ET - Etiopia 8
EU - Europa 8
LB - Libano 8
PE - Perù 8
BO - Bolivia 7
NI - Nicaragua 7
PR - Porto Rico 7
DO - Repubblica Dominicana 6
JM - Giamaica 6
BH - Bahrain 5
CY - Cipro 5
EE - Estonia 5
LK - Sri Lanka 5
LU - Lussemburgo 5
BZ - Belize 4
HN - Honduras 4
HU - Ungheria 4
NG - Nigeria 4
NO - Norvegia 4
SN - Senegal 4
UG - Uganda 4
AM - Armenia 3
DK - Danimarca 3
PA - Panama 3
PS - Palestinian Territory 3
RS - Serbia 3
SI - Slovenia 3
AO - Angola 2
BS - Bahamas 2
CU - Cuba 2
DM - Dominica 2
Totale 37.161
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Città #
Southend 1.851
Singapore 1.424
Santa Clara 1.413
Ashburn 1.393
Fairfield 1.109
Hong Kong 1.023
Woodbridge 992
Chandler 913
Hefei 887
Jacksonville 876
Houston 841
Ann Arbor 784
San Jose 578
Nyköping 555
Dearborn 553
Munich 553
Helsinki 533
London 526
Seattle 459
Wilmington 439
Beijing 433
Dallas 373
Cambridge 355
Chicago 346
New York 327
Los Angeles 321
Berlin 315
Council Bluffs 296
Ho Chi Minh City 279
Modena 259
Seoul 244
Hanoi 230
The Dalles 193
Sofia 177
Eugene 165
Princeton 161
Brussels 159
Milan 156
San Diego 143
Izmir 135
Lauterbourg 131
Des Moines 127
Buffalo 104
Moscow 99
Salt Lake City 95
Dublin 88
Shanghai 88
São Paulo 83
Amsterdam 74
Orem 67
Elk Grove Village 62
Frankfurt am Main 59
Fremont 55
Toronto 54
Tokyo 53
Da Nang 51
Redwood City 50
Tampa 50
Warsaw 47
Columbus 46
Yalova 45
Boardman 44
Rome 42
Norwalk 41
Bremen 40
Guangzhou 38
Philadelphia 36
Bologna 35
Kent 35
Shenzhen 35
Falls Church 33
Haiphong 32
Mexico City 32
Kunming 31
Mumbai 31
Rio de Janeiro 28
West Jordan 28
Jakarta 27
Miano 27
Turku 27
Augusta 26
Paris 26
Sterling 26
Falkenstein 25
Phoenix 25
San Francisco 25
Auckland 24
Belo Horizonte 24
Brooklyn 24
Horia 24
Nanjing 24
Boston 23
Montreal 23
Verona 23
Atlanta 22
Baghdad 22
Jyväskylä 22
Sochi 22
Denver 21
Grafing 21
Totale 25.411
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Nome #
1,2,4-Benzothiadiazine derivatives as alpha(1) and 5-HT1A receptor ligands 977
1 '-Benzyl-3,4-dihydrospiro[2H-1-benzothiopyran-2,4 '-piperidine] (Spipethiane), a potent and highly selective sigma(1) ligand 819
1,3-Diossolani e analoghi aperti come nuovi ligandi per il recettore Sigma 808
1,3-Dioxolane-Based Ligands Incorporating a Lactam or Imide moiety: Structure-Affinity/Activity Relationship at alpha1–Adrenoceptor subtypes and at 5-HT1A Receptors 750
(2,2-difenil-[1,3]-diossolan-4ilmetil)-(3-fenil-propil)-ammina: nuovo agonista parziale del recettore serotoninergico 5-HT1A 644
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity 581
1,3-Dioxolane-Based Ligands as a Novel Class of Alpha1-Adrenoceptor Antagonists 528
1,3-Dioxolane-Based Ligands as Rigid Analogues ofNaftopidil: Structure–Affinity/Activity Relationships at a1and 5-HT1A Receptors 498
1,4-Dioxolane-triazaspirodecanone derivatives as nociceptin/orphanin FQ receptor ligands 453
1,3-dioxolane-based ligands in the search for alpha1-adrenergic antagonists. 449
Enantiomeric resolution of [(2,2-diphenyl-1,3-dioxolan-4-yl)methyl](2-phenoxyethyl)amine, a potent α1and 5-HT1Areceptor ligand: an in vitro and computational study 447
(2,2-Diphenyl-[1,3]oxathiolan-5-ylmethyl)-(3-phenylpropyl)-amine: a Potent and Selective 5-HT1A Receptor Agonist 446
Synthesis and pharmacological evaluation of 1-benzylpiperazine and 4-benzylpiperidine as potent sigma ligands. 440
Discovery of a new 5-HT1A receptor agonist, acting ‘in vivo’ in a rat model of anxiety and depression 428
Development, Validation and Application of an LC-MS/MS Bioanalytical Method for the Quantification of GF449, A Novel 5-HT1A Agonist, in Rat Plasma and Brain. 414
A New and Versatile Synthesis of 1,3-Dioxan-5-yl-pyrimidine and Purine Nucleoside Analogues 394
5-Arylbenzothiadiazine Type Compounds as Positive Allosteric Modulators of AMPA/Kainate Receptors 387
A homology modelling-driven study leading to the discovery of the first mouse trace amine-associated receptor 5 (TAAR5) antagonists 379
Discovery Of New Sigma-2 Receptor Agonist Endowed With Antiproliferative Activity 367
Synthesis and biological evaluations of 4-alkyl-1-Arylpiperazine derivatives: SAR at 5-HT1A and 1 –Adrenoreceptor 360
Synthesis, biological evaluation and molecular modeling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists 350
1-(1,4-Dioxa-spiro[4.5]dec-2ylmethyl)-4-(2-methoxy-phenyl)-piperazine: SAR at alpha1 and 5-HT1A Receptors. 343
Structure-Activity Relationship within a new series of σ1 and σ2 receptor ligands: identification of a novel σ2R agonist (BS148) with selective toxicity against metastatic melanoma 341
Diastereoselective Synthesis of (1,3-Dioxan-4-yl)pyrimidine and Purin Nucleoside Analogues 339
Structure-affinity/activity relationships of 1,4-dioxa-spiro[4.5]decane based ligands at α1 and 5-HT1A receptors 335
Synthesis and structure-activity relationships of 1-aralkyl-4- benzylpiperidine and 1-aralkyl-4-benzylpiperazine derivatives as potent σ ligands 331
Discovery of a new series of 5-HT1A receptor agonists 330
Evaluation of stereo and chemical stability of chiral compounds 329
Efficient synthesis of 5,6-dihydro-8H-[1,2,4]thiadiazino[6,5,4-de] phenanthridine 4,4-dioxide and 5,6-dihydro-8H-[1,2,4]-thiadiazino[6,5,4-ij] thieno[2,3-c]quinoline 4,4-dioxide 319
Synthesis of Heteroaryl ortho-Phenoxyethylamines via Suzuki Cross-Coupling: Easy Access to New Potential Scaffolds in Medicinal Chemistry 317
Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives 317
Investigation of the effect of different linker chemotypes on the inhibition of histone deacetylases (HDACs) 309
Synthesis and biological evaluation of 1,3-dioxolane-based 5-HT 1A receptor agonists for CNS disorders and neuropathic pain 304
Scouting Sigma Receptor Ligands As New Tools For The Treatment Of Neurodegenerative Diseases And Cancer 302
Synthesis, structural characterization and biological evaluation of 4′-C-methyl- and phenyl-dioxolane pyrimidine and purine nucleosides 294
BS148 Reduces the Aggressiveness of Metastatic Melanoma via Sigma-2 Receptor Targeting 289
Further insights into the pharmacology of the human Trace Amine-Associated Receptors: discovery of novel ligands for TAAR1 by a virtual screening approach 287
Synthesis and antimuscarinic activity of some N-(4-dimethylaminomethyl-2-phenyl-1,3)dioxolan-2-ylmethyl)lactam methiodides 281
Synthesis and Antimuscarinic Activity of Some Ether- and Thioether-Bearing 1,3-dioxolanes and Related Sulfoxides and Sulfones 276
Exhaustive CoMFA and CoMSIA analyses around different chemical entities: A ligand-based study exploring the affinity and selectivity profiles of 5-HT1A ligands 276
2-D and 3-D modeling of imidazoline receptor ligands: Insights into pharmacophore 275
Synthesis, biological evaluation and molecular modelling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists 275
Affinity and efficacy correlate with chemical structuremore than potency does in a series of pentatomic cyclicmuscarinic agonists 274
Insights into the structure and pharmacology of the human trace amine-associated receptor 1 (hTAAR1): homology modelling and docking studies 274
Transacetalization of Acetals with Butane-1,2,4-triol Using Cobalt(II) Chloride and Chlorotrimethylsilane 270
Structure-activity relationship at alpha-adrenergic receptors within a series of imidazoline analogues of cirazoline 269
Synthesis and Structure-Activity Relationships of Triazaspirodecanone Derivatives as Nociceptin/Orphanin FQ Receptor Ligands 264
2-(2-phenylcyclopropyl) imidazolines: Reversed enantioselective interaction at I-1 and I-2 imidazoline receptors 261
Derivati 1,3-diossanici come ligandi alpha1 adrenergici e 5-HT1A serotoninergici. 258
Synthesis of 5-Methyl-1,3-oxathiolane-based Nucleoside Analogues as Potential Antiviral Agents 258
Heteroarylphenoxyethyl amine as selective 5-HT1A receptor ligands: synthesis and structure-activity ralationship studies. 254
CONFORMATIONAL AND CONFIGURATIONAL STUDY OF 1,3-DIOXOLANES BY PROTON AND CARBON NMR-SPECTROSCOPY 254
Synthesis, Biological Evaluation and Docking Studies of tetrahydrofuran- cyclopentanone- and cyclopentanol-based ligands acting at Adrenergic alpha1- and Serotonine 5-HT1A receptors 250
Synthesis and antimuscarinic activity of derivatives of 2-substituted-1,3-dioxolanes 249
Benzothiadiazine derivatives as 1 and 5-HT1A receptor ligands. 246
Structure Activity Relationships at 5-HT1A receptors within a novel series of 4-alkyl-1-arylpiperazine derivatives 244
Insights into the structure of the Human TAAR5 receptor: a computational study 244
Pyrrolidine Derivatives as New Ligands for 5-HT1A Receptors 244
Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents 244
Synthesis, enantiomeric separation and docking studies of spiropiperidine analogues as ligands of the nociceptin/orphanin FQ receptor 239
Effect of the rigidification of propranolol, a mixed β-adrenoceptor and 5-HT1AR antagonist 236
Identification of a Potent and Selective 5-HT1AReceptor Agonist with In Vitro and In Vivo Antinociceptive Activity 236
Insights into the structure and pharmacology of Trace Amine-Associated Receptor 1 (TAAR1), a new target for medicinal chemistry 231
Second Joint Italian-Swiss Meeting on Medicinal Chemistry , Italy, Modena 19-20 February 2005. 228
Synthesis, absolute configuration and antimuscarinic activity of the enantiomers of [1-(2,2-diphenyl-[1,3]dioxolan-4-yl)-ethyl]dimethyl-amine 227
Fallot's tetralogy and squatting position 223
Investigation within a new series of heterocyclic biaryl piperazines acting at 5-HT1A serotoninergic receptors 221
An unexpected central hypertensive effect of the new imidazoline compound benazoline 220
Synthesis, Pharmacological Evaluation and Selectivity Profile of Isomeric 2-Phenyl-2-cyclohexyl-4-[(dimethylamino)methyl]-1,3-dithiolane Methiodide as Potent Antimuscarinic Agents 216
Ligand binding to I-2 imidazoline receptor: The role of lipophilicity in quantitative structure-activity relationship models 215
A Novel Class of 1,3-Oxathiolane Nuclosides Analogues Having Potent Anti-HIV Activity. 207
I-1 imidazoline receptor-mediated effects on apoptotic processes in PC12 cells 206
Synthesis, NMR spectroscopy study, and antimuscarinic activity of a series of 2-(acyloxymethyl)-1,3-dioxolanes 206
Effect of the replacement of the o-methoxyphenyl moiety with nitrogen-containing aromatic rings within N-phenyl-piperazine and phenoxy-ethylamine-based 1,3-dioxo/oxathio/dithiolanes as α1 and 5-HT1A receptor ligands 204
Alpha-Adrenoceptor occupancy by N,N-dimethyl-2-bromo-2-phenethylamine hydrobromide (DMPEA) in rat vas deferens 204
Synthesis, structural characterization and pharmacological evaluation of spiroxatrine analogs as potential nociceptin/orphanin FQ receptor ligands 204
Determination of Muscarinic Agonist Potencies at M1 and M2 Muscarinic Receptors in a Modified Pithed Rat 203
Synthesis and Anti-HIV Activity of 1,3-Dithiolane Nucleosides 203
Ring opening effect at alpha1-adrenoceptor subtypes and 5-HT1A receptors within a novel class of 1,3-Dioxolane-based ligands 202
Derivati 1,3-Diossanici come Antagonisti Muscarinici 201
Structure Activity Relationship at 5-HT1A receptors within a novel series of spiro-1,3-Dioxolane-based ligands 200
2-{[(2-(2,6-Dimethoxyphenoxy)ethyl]}-1,4-benzoxathiano:A New Antagonist With High Potency and Selectivity Toward alpha1-Adrenoreceptors. 200
Coupling of I-1 imidazoline receptors to the cAMP pathway: Studies with a highly selective ligand, benazoline 192
Spiroxatrine derivatives towards 5-HT1A receptor selectivity 188
Structure-Activity Relationships in Prazosin-Related Compounds. Effect of Replacing a Piuperazine Ring with an Alkanediamine Moiety on alpa1-Adrenoreceptor Blocking Activity. 187
Synthesis and Pharmacological Evaluation of Some Analogues of the Ca-Antagonist Cinnarizine 187
Pharmacological Characterizazion of Muscarinic Receptor Subtypes in Rabbit Isolated Tissue Preparation 186
Relazioni struttura-attività in una nuova serie di ligandi alpha1-adrenergici e 5-HT1A serotoninergici a struttura 2,2-difenil-[1,3]diossolanica 186
Pyrimidinyl or Purinyl 1,3-Dioxolanes and 1,3-Dithiolanes, Methods for their Preparation and Their Use as Virucides 185
Synthesis and structural characterization of spiroxatrine derivatives as potential non-peptide ligands for NOP receptor 184
Synthesis and structure-activity relationship studies in a series of 2-substituted 1,3-dioxolanes modified at the cationic head 184
IDENTIFICATION OF POTENT 1,3-DIOXOLANE-BASED 5-HT1A RECEPTOR AGONISTS FOR THE TREATMENTS OF CNS DISORDERS AND PAIN 184
Risoluzione della miscela racemica del (±)-(2,2-difenil-[1,3]diossolan-4-ilmetil)-(2-fenossi-etil) ammina, potente antagonista alpha1 adrenergico, 183
Fluoronorepinephrines: further pharmacological evaluation in vitro and in pithed rats 182
The XIXth National Meeting on Medicinal Chemistry: Verona, Italy 181
Effect of aromatic substitution on antimuscarinic activity of 2-phenyl-2-cyclohexyl-4-[(dimethylamino)methyl]-1,3-dioxolanes 179
Imidazoline receptors: Qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity 179
Synthesis and pharmacological evaluation of Spiroxatrine derivatives as potential ligands for NOP receptor 177
Nuova Serie di Ligandi Sigma a Struttura Piperazinica e Piperidinica 175
Pharmacological Characterization of Chiral Muscarinic Antagonists cis-2-Phenyl-2-cyclohexyl-r-5-[(dimethylamino)-methyl]1,3-oxathiolane-3-oxide Methiodide 173
Totale 29.969
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Categoria #
all - tutte 128.526
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 128.526
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.709 116 304 180 291 123 172 92 155 343 203 401 329
2022/20233.074 524 329 180 299 316 464 88 238 378 69 127 62
2023/20241.859 57 108 163 162 465 176 128 241 35 88 91 145
2024/20256.728 288 81 113 404 1.108 854 707 461 903 346 618 845
2025/202611.425 687 570 1.264 1.299 1.559 812 1.214 662 1.065 1.250 551 492
2026/2027304 304 0 0 0 0 0 0 0 0 0 0 0
Totale 37.440