BRASILI, Livio
 Distribuzione geografica
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Continente #
NA - Nord America 16.267
EU - Europa 9.958
AS - Asia 8.186
SA - Sud America 1.210
AF - Africa 162
OC - Oceania 42
Continente sconosciuto - Info sul continente non disponibili 9
Totale 35.834
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Nazione #
US - Stati Uniti d'America 16.004
GB - Regno Unito 2.882
CN - Cina 2.439
SG - Singapore 2.274
DE - Germania 1.538
SE - Svezia 1.339
IT - Italia 1.326
HK - Hong Kong 1.053
BR - Brasile 940
VN - Vietnam 937
FI - Finlandia 724
RU - Federazione Russa 482
UA - Ucraina 435
FR - Francia 363
TR - Turchia 289
IN - India 271
KR - Corea 261
BG - Bulgaria 181
BE - Belgio 162
CA - Canada 147
NL - Olanda 124
IE - Irlanda 93
AR - Argentina 82
BD - Bangladesh 81
ID - Indonesia 75
IQ - Iraq 72
MX - Messico 68
PL - Polonia 67
RO - Romania 62
JP - Giappone 61
EC - Ecuador 49
PK - Pakistan 46
IR - Iran 40
LT - Lituania 40
ES - Italia 37
CO - Colombia 36
IL - Israele 33
ZA - Sudafrica 33
CL - Cile 30
VE - Venezuela 30
PH - Filippine 29
AE - Emirati Arabi Uniti 28
KE - Kenya 24
NZ - Nuova Zelanda 24
SA - Arabia Saudita 23
MA - Marocco 22
EG - Egitto 21
OM - Oman 17
PY - Paraguay 17
AU - Australia 16
TH - Thailandia 16
UZ - Uzbekistan 16
AT - Austria 15
CH - Svizzera 15
BY - Bielorussia 14
JO - Giordania 14
MY - Malesia 14
KZ - Kazakistan 13
TN - Tunisia 13
TW - Taiwan 12
AZ - Azerbaigian 11
DZ - Algeria 11
NP - Nepal 11
CZ - Repubblica Ceca 10
CI - Costa d'Avorio 9
UY - Uruguay 9
AL - Albania 8
ET - Etiopia 8
EU - Europa 8
LB - Libano 8
PT - Portogallo 8
BO - Bolivia 7
CR - Costa Rica 7
PE - Perù 7
DO - Repubblica Dominicana 6
PR - Porto Rico 6
BH - Bahrain 5
CY - Cipro 5
LK - Sri Lanka 5
LU - Lussemburgo 5
NI - Nicaragua 5
BZ - Belize 4
EE - Estonia 4
JM - Giamaica 4
NG - Nigeria 4
NO - Norvegia 4
SN - Senegal 4
UG - Uganda 4
AM - Armenia 3
DK - Danimarca 3
HN - Honduras 3
PA - Panama 3
PS - Palestinian Territory 3
RS - Serbia 3
SI - Slovenia 3
AO - Angola 2
CU - Cuba 2
DM - Dominica 2
GE - Georgia 2
HR - Croazia 2
Totale 35.787
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Città #
Southend 1.851
Singapore 1.409
Santa Clara 1.380
Ashburn 1.173
Fairfield 1.109
Hong Kong 1.013
Woodbridge 992
Chandler 913
Hefei 887
Jacksonville 875
Houston 837
Ann Arbor 784
Nyköping 555
Dearborn 553
Munich 553
Helsinki 533
London 525
Seattle 458
San Jose 452
Wilmington 436
Beijing 424
Dallas 357
Cambridge 355
Chicago 344
Berlin 315
New York 291
Los Angeles 281
Ho Chi Minh City 279
Modena 258
Seoul 243
Hanoi 229
Council Bluffs 193
The Dalles 190
Sofia 177
Eugene 165
Princeton 161
Brussels 159
San Diego 143
Izmir 135
Lauterbourg 131
Des Moines 127
Milan 105
Moscow 99
Buffalo 95
Salt Lake City 95
Dublin 88
Shanghai 85
São Paulo 81
Amsterdam 74
Orem 64
Elk Grove Village 59
Frankfurt am Main 59
Fremont 53
Da Nang 51
Redwood City 50
Tampa 50
Tokyo 49
Toronto 49
Warsaw 47
Yalova 45
Norwalk 41
Boardman 40
Bremen 40
Columbus 38
Guangzhou 38
Philadelphia 36
Kent 35
Shenzhen 35
Bologna 34
Falls Church 33
Haiphong 32
Kunming 31
Mumbai 31
Mexico City 30
Rome 30
Rio de Janeiro 28
West Jordan 28
Jakarta 27
Turku 27
Paris 26
Sterling 26
Falkenstein 25
Phoenix 25
Auckland 24
Augusta 24
Horia 24
Nanjing 24
San Francisco 24
Belo Horizonte 23
Boston 23
Brooklyn 23
Verona 23
Baghdad 22
Jyväskylä 22
Sochi 22
Grafing 21
Leawood 21
Hillsboro 20
Montreal 20
Nairobi 20
Totale 24.659
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Nome #
1,2,4-Benzothiadiazine derivatives as alpha(1) and 5-HT1A receptor ligands 929
1 '-Benzyl-3,4-dihydrospiro[2H-1-benzothiopyran-2,4 '-piperidine] (Spipethiane), a potent and highly selective sigma(1) ligand 805
1,3-Diossolani e analoghi aperti come nuovi ligandi per il recettore Sigma 795
1,3-Dioxolane-Based Ligands Incorporating a Lactam or Imide moiety: Structure-Affinity/Activity Relationship at alpha1–Adrenoceptor subtypes and at 5-HT1A Receptors 745
(2,2-difenil-[1,3]-diossolan-4ilmetil)-(3-fenil-propil)-ammina: nuovo agonista parziale del recettore serotoninergico 5-HT1A 639
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity 568
1,3-Dioxolane-Based Ligands as a Novel Class of Alpha1-Adrenoceptor Antagonists 507
1,3-Dioxolane-Based Ligands as Rigid Analogues ofNaftopidil: Structure–Affinity/Activity Relationships at a1and 5-HT1A Receptors 482
1,3-dioxolane-based ligands in the search for alpha1-adrenergic antagonists. 446
1,4-Dioxolane-triazaspirodecanone derivatives as nociceptin/orphanin FQ receptor ligands 444
(2,2-Diphenyl-[1,3]oxathiolan-5-ylmethyl)-(3-phenylpropyl)-amine: a Potent and Selective 5-HT1A Receptor Agonist 437
Enantiomeric resolution of [(2,2-diphenyl-1,3-dioxolan-4-yl)methyl](2-phenoxyethyl)amine, a potent α1and 5-HT1Areceptor ligand: an in vitro and computational study 435
Discovery of a new 5-HT1A receptor agonist, acting ‘in vivo’ in a rat model of anxiety and depression 425
Synthesis and pharmacological evaluation of 1-benzylpiperazine and 4-benzylpiperidine as potent sigma ligands. 418
Development, Validation and Application of an LC-MS/MS Bioanalytical Method for the Quantification of GF449, A Novel 5-HT1A Agonist, in Rat Plasma and Brain. 402
A New and Versatile Synthesis of 1,3-Dioxan-5-yl-pyrimidine and Purine Nucleoside Analogues 385
5-Arylbenzothiadiazine Type Compounds as Positive Allosteric Modulators of AMPA/Kainate Receptors 382
Discovery Of New Sigma-2 Receptor Agonist Endowed With Antiproliferative Activity 362
A homology modelling-driven study leading to the discovery of the first mouse trace amine-associated receptor 5 (TAAR5) antagonists 355
Synthesis and biological evaluations of 4-alkyl-1-Arylpiperazine derivatives: SAR at 5-HT1A and 1 –Adrenoreceptor 353
1-(1,4-Dioxa-spiro[4.5]dec-2ylmethyl)-4-(2-methoxy-phenyl)-piperazine: SAR at alpha1 and 5-HT1A Receptors. 337
Synthesis, biological evaluation and molecular modeling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists 336
Diastereoselective Synthesis of (1,3-Dioxan-4-yl)pyrimidine and Purin Nucleoside Analogues 330
Structure-Activity Relationship within a new series of σ1 and σ2 receptor ligands: identification of a novel σ2R agonist (BS148) with selective toxicity against metastatic melanoma 329
Structure-affinity/activity relationships of 1,4-dioxa-spiro[4.5]decane based ligands at α1 and 5-HT1A receptors 328
Synthesis and structure-activity relationships of 1-aralkyl-4- benzylpiperidine and 1-aralkyl-4-benzylpiperazine derivatives as potent σ ligands 324
Discovery of a new series of 5-HT1A receptor agonists 318
Evaluation of stereo and chemical stability of chiral compounds 313
Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives 312
Efficient synthesis of 5,6-dihydro-8H-[1,2,4]thiadiazino[6,5,4-de] phenanthridine 4,4-dioxide and 5,6-dihydro-8H-[1,2,4]-thiadiazino[6,5,4-ij] thieno[2,3-c]quinoline 4,4-dioxide 312
Synthesis of Heteroaryl ortho-Phenoxyethylamines via Suzuki Cross-Coupling: Easy Access to New Potential Scaffolds in Medicinal Chemistry 309
Synthesis and biological evaluation of 1,3-dioxolane-based 5-HT 1A receptor agonists for CNS disorders and neuropathic pain 300
Investigation of the effect of different linker chemotypes on the inhibition of histone deacetylases (HDACs) 292
Synthesis, structural characterization and biological evaluation of 4′-C-methyl- and phenyl-dioxolane pyrimidine and purine nucleosides 288
BS148 Reduces the Aggressiveness of Metastatic Melanoma via Sigma-2 Receptor Targeting 284
Synthesis and antimuscarinic activity of some N-(4-dimethylaminomethyl-2-phenyl-1,3)dioxolan-2-ylmethyl)lactam methiodides 274
2-D and 3-D modeling of imidazoline receptor ligands: Insights into pharmacophore 272
Synthesis and Antimuscarinic Activity of Some Ether- and Thioether-Bearing 1,3-dioxolanes and Related Sulfoxides and Sulfones 268
Further insights into the pharmacology of the human Trace Amine-Associated Receptors: discovery of novel ligands for TAAR1 by a virtual screening approach 267
Affinity and efficacy correlate with chemical structuremore than potency does in a series of pentatomic cyclicmuscarinic agonists 266
Structure-activity relationship at alpha-adrenergic receptors within a series of imidazoline analogues of cirazoline 265
Exhaustive CoMFA and CoMSIA analyses around different chemical entities: A ligand-based study exploring the affinity and selectivity profiles of 5-HT1A ligands 263
Transacetalization of Acetals with Butane-1,2,4-triol Using Cobalt(II) Chloride and Chlorotrimethylsilane 262
Scouting Sigma Receptor Ligands As New Tools For The Treatment Of Neurodegenerative Diseases And Cancer 259
Synthesis, biological evaluation and molecular modelling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists 257
2-(2-phenylcyclopropyl) imidazolines: Reversed enantioselective interaction at I-1 and I-2 imidazoline receptors 257
Synthesis and Structure-Activity Relationships of Triazaspirodecanone Derivatives as Nociceptin/Orphanin FQ Receptor Ligands 255
Synthesis of 5-Methyl-1,3-oxathiolane-based Nucleoside Analogues as Potential Antiviral Agents 251
Heteroarylphenoxyethyl amine as selective 5-HT1A receptor ligands: synthesis and structure-activity ralationship studies. 249
CONFORMATIONAL AND CONFIGURATIONAL STUDY OF 1,3-DIOXOLANES BY PROTON AND CARBON NMR-SPECTROSCOPY 249
Structure Activity Relationships at 5-HT1A receptors within a novel series of 4-alkyl-1-arylpiperazine derivatives 240
Benzothiadiazine derivatives as 1 and 5-HT1A receptor ligands. 240
Derivati 1,3-diossanici come ligandi alpha1 adrenergici e 5-HT1A serotoninergici. 237
Insights into the structure and pharmacology of the human trace amine-associated receptor 1 (hTAAR1): homology modelling and docking studies 234
Synthesis and antimuscarinic activity of derivatives of 2-substituted-1,3-dioxolanes 232
Identification of a Potent and Selective 5-HT1AReceptor Agonist with In Vitro and In Vivo Antinociceptive Activity 232
Effect of the rigidification of propranolol, a mixed β-adrenoceptor and 5-HT1AR antagonist 230
Pyrrolidine Derivatives as New Ligands for 5-HT1A Receptors 228
Synthesis, Biological Evaluation and Docking Studies of tetrahydrofuran- cyclopentanone- and cyclopentanol-based ligands acting at Adrenergic alpha1- and Serotonine 5-HT1A receptors 226
Insights into the structure of the Human TAAR5 receptor: a computational study 226
Synthesis, enantiomeric separation and docking studies of spiropiperidine analogues as ligands of the nociceptin/orphanin FQ receptor 225
Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents 225
Synthesis, absolute configuration and antimuscarinic activity of the enantiomers of [1-(2,2-diphenyl-[1,3]dioxolan-4-yl)-ethyl]dimethyl-amine 221
Second Joint Italian-Swiss Meeting on Medicinal Chemistry , Italy, Modena 19-20 February 2005. 220
An unexpected central hypertensive effect of the new imidazoline compound benazoline 219
Investigation within a new series of heterocyclic biaryl piperazines acting at 5-HT1A serotoninergic receptors 216
Ligand binding to I-2 imidazoline receptor: The role of lipophilicity in quantitative structure-activity relationship models 210
Synthesis, Pharmacological Evaluation and Selectivity Profile of Isomeric 2-Phenyl-2-cyclohexyl-4-[(dimethylamino)methyl]-1,3-dithiolane Methiodide as Potent Antimuscarinic Agents 207
I-1 imidazoline receptor-mediated effects on apoptotic processes in PC12 cells 203
A Novel Class of 1,3-Oxathiolane Nuclosides Analogues Having Potent Anti-HIV Activity. 203
Synthesis, NMR spectroscopy study, and antimuscarinic activity of a series of 2-(acyloxymethyl)-1,3-dioxolanes 202
Alpha-Adrenoceptor occupancy by N,N-dimethyl-2-bromo-2-phenethylamine hydrobromide (DMPEA) in rat vas deferens 200
Synthesis and Anti-HIV Activity of 1,3-Dithiolane Nucleosides 197
Structure Activity Relationship at 5-HT1A receptors within a novel series of spiro-1,3-Dioxolane-based ligands 197
Synthesis, structural characterization and pharmacological evaluation of spiroxatrine analogs as potential nociceptin/orphanin FQ receptor ligands 197
Derivati 1,3-Diossanici come Antagonisti Muscarinici 197
Insights into the structure and pharmacology of Trace Amine-Associated Receptor 1 (TAAR1), a new target for medicinal chemistry 195
Determination of Muscarinic Agonist Potencies at M1 and M2 Muscarinic Receptors in a Modified Pithed Rat 194
Ring opening effect at alpha1-adrenoceptor subtypes and 5-HT1A receptors within a novel class of 1,3-Dioxolane-based ligands 194
2-{[(2-(2,6-Dimethoxyphenoxy)ethyl]}-1,4-benzoxathiano:A New Antagonist With High Potency and Selectivity Toward alpha1-Adrenoreceptors. 193
Fallot's tetralogy and squatting position 192
Coupling of I-1 imidazoline receptors to the cAMP pathway: Studies with a highly selective ligand, benazoline 187
Relazioni struttura-attività in una nuova serie di ligandi alpha1-adrenergici e 5-HT1A serotoninergici a struttura 2,2-difenil-[1,3]diossolanica 184
Synthesis and Pharmacological Evaluation of Some Analogues of the Ca-Antagonist Cinnarizine 182
Structure-Activity Relationships in Prazosin-Related Compounds. Effect of Replacing a Piuperazine Ring with an Alkanediamine Moiety on alpa1-Adrenoreceptor Blocking Activity. 181
Pharmacological Characterizazion of Muscarinic Receptor Subtypes in Rabbit Isolated Tissue Preparation 181
Synthesis and structure-activity relationship studies in a series of 2-substituted 1,3-dioxolanes modified at the cationic head 181
Risoluzione della miscela racemica del (±)-(2,2-difenil-[1,3]diossolan-4-ilmetil)-(2-fenossi-etil) ammina, potente antagonista alpha1 adrenergico, 181
Spiroxatrine derivatives towards 5-HT1A receptor selectivity 180
Pyrimidinyl or Purinyl 1,3-Dioxolanes and 1,3-Dithiolanes, Methods for their Preparation and Their Use as Virucides 179
Synthesis and structural characterization of spiroxatrine derivatives as potential non-peptide ligands for NOP receptor 179
Fluoronorepinephrines: further pharmacological evaluation in vitro and in pithed rats 177
The XIXth National Meeting on Medicinal Chemistry: Verona, Italy 176
Effect of aromatic substitution on antimuscarinic activity of 2-phenyl-2-cyclohexyl-4-[(dimethylamino)methyl]-1,3-dioxolanes 174
IDENTIFICATION OF POTENT 1,3-DIOXOLANE-BASED 5-HT1A RECEPTOR AGONISTS FOR THE TREATMENTS OF CNS DISORDERS AND PAIN 174
Imidazoline receptors: Qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity 173
Pharmacological Characterization of Chiral Muscarinic Antagonists cis-2-Phenyl-2-cyclohexyl-r-5-[(dimethylamino)-methyl]1,3-oxathiolane-3-oxide Methiodide 173
Nuova Serie di Ligandi Sigma a Struttura Piperazinica e Piperidinica 171
Synthesis and pharmacological evaluation of Spiroxatrine derivatives as potential ligands for NOP receptor 167
N,N"-(DITHIO-2,1-ETIIANEDIYL)BIS{N'-(PYRROL-2-YLMETI{YL)-1,6-HEXANEDIAMINE}(PYREXTRAMINE), A NEW IRREVERSIBLE a,.ADRENORECEPTOR BLOCKING AGENTTHE TETRAMINE DISULFIDE CLASS 167
Totale 28.939
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Categoria #
all - tutte 119.618
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 119.618
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021730 0 0 0 0 0 0 0 0 0 382 220 128
2021/20222.709 116 304 180 291 123 172 92 155 343 203 401 329
2022/20233.074 524 329 180 299 316 464 88 238 378 69 127 62
2023/20241.859 57 108 163 162 465 176 128 241 35 88 91 145
2024/20256.728 288 81 113 404 1.108 854 707 461 903 346 618 845
2025/202610.350 687 570 1.264 1.299 1.559 812 1.214 662 1.065 1.218 0 0
Totale 36.061