BRASILI, Livio
 Distribuzione geografica
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Continente #
NA - Nord America 20.490
EU - Europa 10.287
AS - Asia 8.498
SA - Sud America 1.277
Continente sconosciuto - Info sul continente non disponibili 242
AF - Africa 169
OC - Oceania 42
Totale 41.005
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Nazione #
US - Stati Uniti d'America 20.022
GB - Regno Unito 2.901
CN - Cina 2.482
SG - Singapore 2.325
IT - Italia 1.589
DE - Germania 1.540
SE - Svezia 1.346
HK - Hong Kong 1.068
BR - Brasile 989
VN - Vietnam 938
FI - Finlandia 724
RU - Federazione Russa 486
UA - Ucraina 435
FR - Francia 368
TR - Turchia 290
IN - India 278
CA - Canada 263
KR - Corea 262
BD - Bangladesh 252
BG - Bulgaria 181
BE - Belgio 162
NL - Olanda 127
IE - Irlanda 93
AR - Argentina 86
ID - Indonesia 80
MX - Messico 74
IQ - Iraq 73
PL - Polonia 68
JP - Giappone 66
RO - Romania 62
EC - Ecuador 49
PK - Pakistan 47
CO - Colombia 44
ES - Italia 44
IR - Iran 40
LT - Lituania 40
IL - Israele 37
ZA - Sudafrica 33
CL - Cile 32
PH - Filippine 31
VE - Venezuela 31
AE - Emirati Arabi Uniti 30
KE - Kenya 25
NZ - Nuova Zelanda 24
CR - Costa Rica 23
SA - Arabia Saudita 23
MA - Marocco 22
EG - Egitto 21
JM - Giamaica 19
PY - Paraguay 18
OM - Oman 17
AU - Australia 16
CH - Svizzera 16
TH - Thailandia 16
UZ - Uzbekistan 16
AT - Austria 15
BY - Bielorussia 14
JO - Giordania 14
MY - Malesia 14
EE - Estonia 13
KZ - Kazakistan 13
TN - Tunisia 13
TW - Taiwan 13
GT - Guatemala 12
PR - Porto Rico 12
AZ - Azerbaigian 11
DZ - Algeria 11
NI - Nicaragua 11
NP - Nepal 11
CZ - Repubblica Ceca 10
CI - Costa d'Avorio 9
HN - Honduras 9
PT - Portogallo 9
UY - Uruguay 9
AL - Albania 8
ET - Etiopia 8
EU - Europa 8
LB - Libano 8
PE - Perù 8
TT - Trinidad e Tobago 8
BO - Bolivia 7
SV - El Salvador 7
CW - ???statistics.table.value.countryCode.CW??? 6
DK - Danimarca 6
DO - Repubblica Dominicana 6
BH - Bahrain 5
CY - Cipro 5
LK - Sri Lanka 5
LU - Lussemburgo 5
SC - Seychelles 5
UG - Uganda 5
BZ - Belize 4
HU - Ungheria 4
NG - Nigeria 4
NO - Norvegia 4
PS - Palestinian Territory 4
SN - Senegal 4
AG - Antigua e Barbuda 3
AM - Armenia 3
GP - Guadalupe 3
Totale 40.710
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Città #
Ashburn 2.547
Southend 1.851
Santa Clara 1.454
Singapore 1.430
Fairfield 1.109
Hong Kong 1.026
Woodbridge 992
Chandler 913
San Jose 890
Hefei 887
Jacksonville 877
Houston 847
Ann Arbor 784
Council Bluffs 676
Nyköping 555
Dearborn 553
Munich 553
Helsinki 533
London 527
Seattle 463
Wilmington 443
Beijing 433
Dallas 390
New York 368
Chicago 362
Cambridge 360
Los Angeles 354
Berlin 315
Ho Chi Minh City 279
Modena 259
Seoul 244
Hanoi 230
The Dalles 194
Milan 177
Sofia 177
Eugene 166
Princeton 161
Brussels 159
San Diego 148
Izmir 135
Lauterbourg 131
Des Moines 128
Buffalo 127
São Paulo 118
Columbus 111
Washington 108
Moscow 99
Salt Lake City 96
Shanghai 89
Dublin 88
Toronto 87
Amsterdam 74
Orem 69
Elk Grove Village 63
Frankfurt am Main 59
Fremont 56
Tokyo 54
Tampa 53
Phoenix 52
Da Nang 51
Redwood City 50
Philadelphia 48
Rome 48
Warsaw 47
Boardman 46
Yalova 45
Norwalk 43
Bremen 40
Bologna 38
Guangzhou 38
Kent 36
Brooklyn 35
Shenzhen 35
Atlanta 34
Denver 34
Mexico City 34
Mumbai 34
Falls Church 33
Haiphong 32
Naples 32
Kunming 31
Rio de Janeiro 28
San Francisco 28
West Jordan 28
Augusta 27
Boston 27
Jakarta 27
Miano 27
Montreal 27
Paris 27
Turku 27
Miami 26
Sterling 26
Falkenstein 25
Auckland 24
Belo Horizonte 24
Hillsboro 24
Horia 24
Nanjing 24
Verona 24
Totale 27.841
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Nome #
1,2,4-Benzothiadiazine derivatives as alpha(1) and 5-HT1A receptor ligands 1.012
1 '-Benzyl-3,4-dihydrospiro[2H-1-benzothiopyran-2,4 '-piperidine] (Spipethiane), a potent and highly selective sigma(1) ligand 850
1,3-Diossolani e analoghi aperti come nuovi ligandi per il recettore Sigma 838
1,3-Dioxolane-Based Ligands Incorporating a Lactam or Imide moiety: Structure-Affinity/Activity Relationship at alpha1–Adrenoceptor subtypes and at 5-HT1A Receptors 773
(2,2-difenil-[1,3]-diossolan-4ilmetil)-(3-fenil-propil)-ammina: nuovo agonista parziale del recettore serotoninergico 5-HT1A 663
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity 601
1,3-Dioxolane-Based Ligands as a Novel Class of Alpha1-Adrenoceptor Antagonists 550
1,3-Dioxolane-Based Ligands as Rigid Analogues ofNaftopidil: Structure–Affinity/Activity Relationships at a1and 5-HT1A Receptors 524
1,4-Dioxolane-triazaspirodecanone derivatives as nociceptin/orphanin FQ receptor ligands 478
1,3-dioxolane-based ligands in the search for alpha1-adrenergic antagonists. 467
(2,2-Diphenyl-[1,3]oxathiolan-5-ylmethyl)-(3-phenylpropyl)-amine: a Potent and Selective 5-HT1A Receptor Agonist 464
Synthesis and pharmacological evaluation of 1-benzylpiperazine and 4-benzylpiperidine as potent sigma ligands. 461
Enantiomeric resolution of [(2,2-diphenyl-1,3-dioxolan-4-yl)methyl](2-phenoxyethyl)amine, a potent α1and 5-HT1Areceptor ligand: an in vitro and computational study 458
Discovery of a new 5-HT1A receptor agonist, acting ‘in vivo’ in a rat model of anxiety and depression 448
Development, Validation and Application of an LC-MS/MS Bioanalytical Method for the Quantification of GF449, A Novel 5-HT1A Agonist, in Rat Plasma and Brain. 437
A New and Versatile Synthesis of 1,3-Dioxan-5-yl-pyrimidine and Purine Nucleoside Analogues 412
A homology modelling-driven study leading to the discovery of the first mouse trace amine-associated receptor 5 (TAAR5) antagonists 406
5-Arylbenzothiadiazine Type Compounds as Positive Allosteric Modulators of AMPA/Kainate Receptors 401
Synthesis and biological evaluations of 4-alkyl-1-Arylpiperazine derivatives: SAR at 5-HT1A and 1 –Adrenoreceptor 396
Discovery Of New Sigma-2 Receptor Agonist Endowed With Antiproliferative Activity 387
Synthesis, biological evaluation and molecular modeling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists 373
Diastereoselective Synthesis of (1,3-Dioxan-4-yl)pyrimidine and Purin Nucleoside Analogues 367
1-(1,4-Dioxa-spiro[4.5]dec-2ylmethyl)-4-(2-methoxy-phenyl)-piperazine: SAR at alpha1 and 5-HT1A Receptors. 357
Structure-Activity Relationship within a new series of σ1 and σ2 receptor ligands: identification of a novel σ2R agonist (BS148) with selective toxicity against metastatic melanoma 355
Synthesis and antimuscarinic activity of some N-(4-dimethylaminomethyl-2-phenyl-1,3)dioxolan-2-ylmethyl)lactam methiodides 354
Synthesis and structure-activity relationships of 1-aralkyl-4- benzylpiperidine and 1-aralkyl-4-benzylpiperazine derivatives as potent σ ligands 354
Structure-affinity/activity relationships of 1,4-dioxa-spiro[4.5]decane based ligands at α1 and 5-HT1A receptors 353
Efficient synthesis of 5,6-dihydro-8H-[1,2,4]thiadiazino[6,5,4-de] phenanthridine 4,4-dioxide and 5,6-dihydro-8H-[1,2,4]-thiadiazino[6,5,4-ij] thieno[2,3-c]quinoline 4,4-dioxide 351
Discovery of a new series of 5-HT1A receptor agonists 349
Further insights into the pharmacology of the human Trace Amine-Associated Receptors: discovery of novel ligands for TAAR1 by a virtual screening approach 347
Evaluation of stereo and chemical stability of chiral compounds 345
Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives 336
Synthesis of Heteroaryl ortho-Phenoxyethylamines via Suzuki Cross-Coupling: Easy Access to New Potential Scaffolds in Medicinal Chemistry 333
Scouting Sigma Receptor Ligands As New Tools For The Treatment Of Neurodegenerative Diseases And Cancer 325
Investigation of the effect of different linker chemotypes on the inhibition of histone deacetylases (HDACs) 325
Insights into the structure and pharmacology of the human trace amine-associated receptor 1 (hTAAR1): homology modelling and docking studies 320
BS148 Reduces the Aggressiveness of Metastatic Melanoma via Sigma-2 Receptor Targeting 319
Synthesis and biological evaluation of 1,3-dioxolane-based 5-HT 1A receptor agonists for CNS disorders and neuropathic pain 315
Synthesis, structural characterization and biological evaluation of 4′-C-methyl- and phenyl-dioxolane pyrimidine and purine nucleosides 312
Synthesis, biological evaluation and molecular modelling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists 305
Synthesis and Antimuscarinic Activity of Some Ether- and Thioether-Bearing 1,3-dioxolanes and Related Sulfoxides and Sulfones 295
Exhaustive CoMFA and CoMSIA analyses around different chemical entities: A ligand-based study exploring the affinity and selectivity profiles of 5-HT1A ligands 294
2-D and 3-D modeling of imidazoline receptor ligands: Insights into pharmacophore 293
Affinity and efficacy correlate with chemical structuremore than potency does in a series of pentatomic cyclicmuscarinic agonists 293
Synthesis and Structure-Activity Relationships of Triazaspirodecanone Derivatives as Nociceptin/Orphanin FQ Receptor Ligands 288
Structure-activity relationship at alpha-adrenergic receptors within a series of imidazoline analogues of cirazoline 288
Transacetalization of Acetals with Butane-1,2,4-triol Using Cobalt(II) Chloride and Chlorotrimethylsilane 287
Synthesis of 5-Methyl-1,3-oxathiolane-based Nucleoside Analogues as Potential Antiviral Agents 282
2-(2-phenylcyclopropyl) imidazolines: Reversed enantioselective interaction at I-1 and I-2 imidazoline receptors 282
Synthesis and antimuscarinic activity of derivatives of 2-substituted-1,3-dioxolanes 278
Derivati 1,3-diossanici come ligandi alpha1 adrenergici e 5-HT1A serotoninergici. 277
Insights into the structure of the Human TAAR5 receptor: a computational study 275
CONFORMATIONAL AND CONFIGURATIONAL STUDY OF 1,3-DIOXOLANES BY PROTON AND CARBON NMR-SPECTROSCOPY 274
Synthesis, Biological Evaluation and Docking Studies of tetrahydrofuran- cyclopentanone- and cyclopentanol-based ligands acting at Adrenergic alpha1- and Serotonine 5-HT1A receptors 272
Heteroarylphenoxyethyl amine as selective 5-HT1A receptor ligands: synthesis and structure-activity ralationship studies. 271
Synthesis, Pharmacological Evaluation and Selectivity Profile of Isomeric 2-Phenyl-2-cyclohexyl-4-[(dimethylamino)methyl]-1,3-dithiolane Methiodide as Potent Antimuscarinic Agents 265
Structure Activity Relationships at 5-HT1A receptors within a novel series of 4-alkyl-1-arylpiperazine derivatives 264
Benzothiadiazine derivatives as 1 and 5-HT1A receptor ligands. 263
Ring opening effect at alpha1-adrenoceptor subtypes and 5-HT1A receptors within a novel class of 1,3-Dioxolane-based ligands 261
Effect of the rigidification of propranolol, a mixed β-adrenoceptor and 5-HT1AR antagonist 257
Pyrrolidine Derivatives as New Ligands for 5-HT1A Receptors 256
Synthesis, enantiomeric separation and docking studies of spiropiperidine analogues as ligands of the nociceptin/orphanin FQ receptor 255
Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents 254
Effect of aromatic substitution on antimuscarinic activity of 2-phenyl-2-cyclohexyl-4-[(dimethylamino)methyl]-1,3-dioxolanes 253
Investigation within a new series of heterocyclic biaryl piperazines acting at 5-HT1A serotoninergic receptors 251
Insights into the structure and pharmacology of Trace Amine-Associated Receptor 1 (TAAR1), a new target for medicinal chemistry 250
Identification of a Potent and Selective 5-HT1AReceptor Agonist with In Vitro and In Vivo Antinociceptive Activity 250
Fallot's tetralogy and squatting position 247
Alpha-Adrenoceptor occupancy by N,N-dimethyl-2-bromo-2-phenethylamine hydrobromide (DMPEA) in rat vas deferens 244
Determination of Muscarinic Agonist Potencies at M1 and M2 Muscarinic Receptors in a Modified Pithed Rat 243
Second Joint Italian-Swiss Meeting on Medicinal Chemistry , Italy, Modena 19-20 February 2005. 242
Synthesis, absolute configuration and antimuscarinic activity of the enantiomers of [1-(2,2-diphenyl-[1,3]dioxolan-4-yl)-ethyl]dimethyl-amine 241
Synthesis, NMR spectroscopy study, and antimuscarinic activity of a series of 2-(acyloxymethyl)-1,3-dioxolanes 237
Ligand binding to I-2 imidazoline receptor: The role of lipophilicity in quantitative structure-activity relationship models 236
Pharmacological Characterization of Chiral Muscarinic Antagonists cis-2-Phenyl-2-cyclohexyl-r-5-[(dimethylamino)-methyl]1,3-oxathiolane-3-oxide Methiodide 234
An unexpected central hypertensive effect of the new imidazoline compound benazoline 232
Synthesis, structural characterization and pharmacological evaluation of spiroxatrine analogs as potential nociceptin/orphanin FQ receptor ligands 232
A Novel Class of 1,3-Oxathiolane Nuclosides Analogues Having Potent Anti-HIV Activity. 232
Coupling of I-1 imidazoline receptors to the cAMP pathway: Studies with a highly selective ligand, benazoline 230
Correlation hetween adrenergic alpha-receptorantagonists of tetramine disulfidesand benzodioxanes classes 229
Effect of the replacement of the o-methoxyphenyl moiety with nitrogen-containing aromatic rings within N-phenyl-piperazine and phenoxy-ethylamine-based 1,3-dioxo/oxathio/dithiolanes as α1 and 5-HT1A receptor ligands 225
Synthesis and Anti-HIV Activity of 1,3-Dithiolane Nucleosides 223
Molecular properties of the adrenergic alpha-receptors.4.Topographical and structural differences betweentissue-specific binding sites as revealedby benextramine and analogues. 223
2-{[(2-(2,6-Dimethoxyphenoxy)ethyl]}-1,4-benzoxathiano:A New Antagonist With High Potency and Selectivity Toward alpha1-Adrenoreceptors. 222
Pharmacological Characterizazion of Muscarinic Receptor Subtypes in Rabbit Isolated Tissue Preparation 218
Structure-Activity Relationships in Prazosin-Related Compounds. Effect of Replacing a Piuperazine Ring with an Alkanediamine Moiety on alpa1-Adrenoreceptor Blocking Activity. 214
MOLECULAR REQUIREMENTS OF THE ACTIVE SITESOF THE CHOLINERGIC RECEPTORSXII (*) - 3-Methyl-2-oxo-L-dimethylaminomethylcyclopentane methiodideas a new selective agonist for the nicotinic receptorM. GIANNELLA, P. ANGELI, C. MELCHIORRE, L. BRASILI 214
Derivati 1,3-Diossanici come Antagonisti Muscarinici 214
I-1 imidazoline receptor-mediated effects on apoptotic processes in PC12 cells 213
Structure Activity Relationship at 5-HT1A receptors within a novel series of spiro-1,3-Dioxolane-based ligands 210
Synthesis and structural characterization of spiroxatrine derivatives as potential non-peptide ligands for NOP receptor 206
Synthesis and structure-activity relationship studies in a series of 2-substituted 1,3-dioxolanes modified at the cationic head 204
Synthesis and pharmacological evaluation of Spiroxatrine derivatives as potential ligands for NOP receptor 202
Synthesis and Pharmacological Evaluation of Some Analogues of the Ca-Antagonist Cinnarizine 202
Risoluzione della miscela racemica del (±)-(2,2-difenil-[1,3]diossolan-4-ilmetil)-(2-fenossi-etil) ammina, potente antagonista alpha1 adrenergico, 202
Pyrimidinyl or Purinyl 1,3-Dioxolanes and 1,3-Dithiolanes, Methods for their Preparation and Their Use as Virucides 201
The XIXth National Meeting on Medicinal Chemistry: Verona, Italy 200
Spiroxatrine derivatives towards 5-HT1A receptor selectivity 199
Imidazoline receptors: Qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity 197
Fluoronorepinephrines: further pharmacological evaluation in vitro and in pithed rats 196
Totale 32.413
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Categoria #
all - tutte 139.201
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 139.201
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.109 0 0 0 291 123 172 92 155 343 203 401 329
2022/20233.074 524 329 180 299 316 464 88 238 378 69 127 62
2023/20241.859 57 108 163 162 465 176 128 241 35 88 91 145
2024/20256.728 288 81 113 404 1.108 854 707 461 903 346 618 845
2025/202611.425 687 570 1.264 1.299 1.559 812 1.214 662 1.065 1.250 551 492
2026/20273.869 374 682 1.239 1.574 0 0 0 0 0 0 0 0
Totale 41.005