RASTELLI, Giulio
 Distribuzione geografica
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Continente #
NA - Nord America 20.047
AS - Asia 9.467
EU - Europa 8.760
SA - Sud America 1.491
AF - Africa 217
OC - Oceania 51
Continente sconosciuto - Info sul continente non disponibili 10
Totale 40.043
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Nazione #
US - Stati Uniti d'America 19.742
SG - Singapore 3.011
GB - Regno Unito 2.614
CN - Cina 2.571
IT - Italia 1.461
BR - Brasile 1.158
HK - Hong Kong 1.156
VN - Vietnam 1.129
SE - Svezia 979
DE - Germania 942
FI - Finlandia 513
RU - Federazione Russa 431
UA - Ucraina 392
PL - Polonia 364
FR - Francia 297
KR - Corea 269
TR - Turchia 265
IN - India 228
ID - Indonesia 170
BG - Bulgaria 165
NL - Olanda 141
BD - Bangladesh 139
CA - Canada 137
AR - Argentina 121
MX - Messico 103
ES - Italia 91
JP - Giappone 77
IQ - Iraq 71
BE - Belgio 67
IE - Irlanda 59
ZA - Sudafrica 54
PK - Pakistan 52
LT - Lituania 49
AU - Australia 47
EC - Ecuador 46
CO - Colombia 44
AE - Emirati Arabi Uniti 41
AT - Austria 39
VE - Venezuela 36
CL - Cile 33
MA - Marocco 33
UZ - Uzbekistan 33
EG - Egitto 28
SA - Arabia Saudita 27
PH - Filippine 23
IR - Iran 22
JO - Giordania 21
KE - Kenya 21
CH - Svizzera 20
RO - Romania 20
AZ - Azerbaigian 17
TN - Tunisia 17
UY - Uruguay 17
DO - Repubblica Dominicana 15
MY - Malesia 15
PY - Paraguay 15
IL - Israele 14
TH - Thailandia 14
KZ - Kazakistan 13
NP - Nepal 13
DZ - Algeria 12
PT - Portogallo 12
HU - Ungheria 11
AL - Albania 10
RS - Serbia 10
BY - Bielorussia 9
CI - Costa d'Avorio 9
HR - Croazia 9
NG - Nigeria 9
NO - Norvegia 9
PE - Perù 9
TW - Taiwan 9
BO - Bolivia 8
GR - Grecia 8
KH - Cambogia 8
LK - Sri Lanka 8
OM - Oman 8
PR - Porto Rico 8
SK - Slovacchia (Repubblica Slovacca) 8
SN - Senegal 8
ET - Etiopia 7
EU - Europa 7
HN - Honduras 7
AO - Angola 6
CZ - Repubblica Ceca 6
LB - Libano 6
PA - Panama 6
TT - Trinidad e Tobago 6
BH - Bahrain 5
CR - Costa Rica 5
CY - Cipro 5
QA - Qatar 5
DK - Danimarca 4
JM - Giamaica 4
NI - Nicaragua 4
SI - Slovenia 4
BB - Barbados 3
GE - Georgia 3
LA - Repubblica Popolare Democratica del Laos 3
LU - Lussemburgo 3
Totale 39.983
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Città #
Fairfield 2.310
Santa Clara 1.885
Ashburn 1.867
Southend 1.720
Singapore 1.604
Woodbridge 1.291
Hong Kong 1.126
Houston 1.017
Chandler 1.007
Seattle 913
Hefei 896
Cambridge 801
Jacksonville 750
Wilmington 741
Ann Arbor 603
Dearborn 577
Nyköping 572
San Jose 516
London 492
Beijing 453
Helsinki 364
Council Bluffs 363
Ho Chi Minh City 362
Warsaw 349
Hanoi 279
Modena 254
Los Angeles 252
Seoul 248
The Dalles 225
Chicago 201
San Diego 189
Milan 170
Princeton 169
Dallas 168
New York 167
Sofia 158
Munich 145
Eugene 135
Lauterbourg 125
Berlin 118
Izmir 116
Jakarta 116
Des Moines 101
Bologna 99
São Paulo 96
Shanghai 94
Frankfurt am Main 86
Salt Lake City 84
Moscow 82
Buffalo 80
Orem 71
Tokyo 61
Brussels 58
Dublin 54
Rome 48
Mexico City 45
Porto Alegre 44
Da Nang 43
Chennai 41
Amsterdam 40
Columbus 40
Guangzhou 40
Haiphong 40
Reggio Emilia 40
Tampa 39
Bremen 38
Redwood City 38
Boardman 37
Elk Grove Village 37
Toronto 37
Kent 36
Rio de Janeiro 35
Falls Church 34
Atlanta 33
Groningen 32
Denver 30
Phoenix 30
Parma 28
Tashkent 28
Baghdad 27
Nuremberg 27
Biên Hòa 26
Paris 26
Johannesburg 25
Norwalk 25
Hải Dương 24
Montreal 24
San Francisco 24
Belo Horizonte 23
Brooklyn 23
Nanjing 23
Poplar 23
Redondo Beach 23
Canberra 22
Saint Petersburg 22
Stockholm 22
Yalova 22
Barcelona 21
Dhaka 21
Washington 21
Totale 28.207
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Nome #
The 1,2,3-triazole ring as a bioisostere in medicinal chemistry 1.275
1-Benzopyran-4-one antioxidants as aldose reductase inhibitors 457
Structural models and binding site prediction of the C-terminal domain of human Hsp90: a new target for anticancer drugs 423
7-Hydroxy-2-substituted-4-H-1-benzopyran-4-one derivatives as aldose reductase inhibitors: a SAR study 418
Polypharmacology: challenges and opportunities in drug discovery 395
BEAR, a Molecular Docking Refinement and Rescoring Method 374
Synthesis and biological activities of novel 17-aminogeldanamycin derivatives 372
An unexpected reversal in the pharmacological stereoselectivity of benzothiadiazine AMPA positive allosteric modulators 363
A rational approach to the design of flavones as xanthine oxidase inhibitors 362
Analytical and Simulation-Based Models for Drug Release and Gel-Degradation in a Tetra-PEG Hydrogel Drug-Delivery System 362
Fruits of ribes, rubus, vaccinium and prunus genus. Metal contents and genome 344
Application of a post-docking procedure based on MM-PBSA and MM-GBSA on single and multiple protein conformations 344
Aldose reductase does catalyse the reduction of glyceraldehyde through a stoichiometric oxidation of NADPH. 340
A model of the interaction of substrates and inhibitors with xanthine oxidase 332
Discovery of Multitarget Antivirals Acting on Both the Dengue Virus NS5-NS3 Interaction and the Host Src/Fyn Kinases 324
Role of bifidobacteria in the hydrolysis of chlorogenic acid 324
Conformational analysis of phthalein derivatives acting as thymidylate synthase inhibitors by means of 1H NMR and quantum chemical calculations 323
Activity prediction and structural insights of Extracellular Signal-Regulated Kinase 2 inhibitors with molecular dynamics simulations 320
Activity of polyphenolic crude extracts as scavengers of superoxide radicals and inhibitors of xanthine oxidase 318
Advances and applications of binding affinity prediction methods in drug discovery 318
Synthesis, activity, and molecular modeling of a new series of tricyclic pyridazinones as selective aldose reductase inhibitors 316
Structure-Based Design of Potent Aromatase Inhibitors by High-Throughput Docking 315
A computational workflow for the design of irreversible inhibitors of protein kinases 312
1H-NMR conformational studies of some phtalein derivatives acting as thymidylate synthase inhibitors 309
On the integration of in silico drug design methods for drug repurposing 306
Selection of protein conformations for structure-based polypharmacology studies 306
BEAR, a novel virtual screening methodology for drug discovery 304
Binding of 1-benzopyran-4-one derivatives to aldose reductase: A free energy perturbation study 304
Molecular dynamics simulations and classical multidimensional scaling unveil new metastable states in the conformational landscape of CDK2 299
Investigation of the effect of different linker chemotypes on the inhibition of histone deacetylases (HDACs) 296
New aldose reductase inhibitors as potential agents for the prevention of long-term diabetic complications 295
Theoretical analysis of the addition of hydroxylamine to uracil and 5-fluorouracil as a model for the Thymidylate synthase reaction 289
Valutazione tossicologica di due nuovi inibitori della DHFR del P. falciparum e del P. vivax 288
WISDOM-II: Screening against multiple targets implicated in malaria using computational grid infrastructures 288
Binding estimation after refinement, a new automated procedure for the refinement and rescoring of docked ligands in virtual screening 286
Grid-enabled high throughput virtual screening 284
Structure-based design of an inhibitor modeled at the substrate active site of aldose reductase 283
Mutational analysis of Plasmodium falciparum dihydrofolate reductase: the role of aspartate 54 and phenylalanine 223 on catalytic activity and antifolate binding 280
Fruit of ribes, rubus, vaccinium and prunus genus, metals content and genome 280
Molecular docking: Shifting paradigms in drug discovery 280
Insights into the interaction of negative allosteric modulators with the metabotropic glutamate receptor 5: Discovery and computational modeling of a new series of ligands with nanomolar affinity 278
Validation of an automated procedure for the prediction of relative free energies of binding on a set of aldose reductase inhibitors 278
Identification of small-molecule EGFR allosteric inhibitors by high-Throughput docking 278
Structural bases for the inhibition of aldose reductase by phenolic compounds 276
Heat shock protein 90 and serine/threonine kinase B-Raf inhibitors have overlapping chemical space 276
Identification of Target Associations for Polypharmacology from Analysis of Crystallographic Ligands of the Protein Data Bank 274
Diabetes complications and their potential prevention: Aldose reductase inhibition and other approaches 273
A series of diarylsubstituted oximes as potential substrates for new aldose reductase inhibitors 272
αC helix displacement as a general approach for allosteric modulation of protein kinases 268
Antifungal Activity and DNA Topoisomerase Inhibition of Hydrolysable Tannins from Punica granatum L. 268
Structure-based discovery of the first allosteric inhibitors of cyclin-dependent kinase 2 266
Exploring the binding site of C-terminal Hsp90 inhibitors 266
Structure–Activity Relationships of Hexahydrocyclopenta[c]quinoline Derivatives as Allosteric Inhibitors of CDK2 and EGFR 266
In vitro effects of Plasmodium falciparum dihydrofolate reductase inhibitors on normal and cancer cell proliferation 264
Preparation of thieno[3,2-h]cinnolinones as matrix metalloproteinase inhibitors 263
Fast and accurate predictions of relative binding free energies using MM-PBSA and MM-GBSA 263
Virtual screening on large scale grids 262
Promiscuity of inhibitors of human protein kinases at varying data confidence levels and test frequencies 262
Drug Repurposing and Polypharmacology to Fight SARS-CoV-2 Through Inhibition of the Main Protease 262
Computational polypharmacology analysis of the heat shock protein 90 interactome 260
ANTHOCYANIDINES AS INHIBITORS OF XANTHINE-OXIDASE 259
Investigating the Selectivity of Allosteric Inhibitors for Mutant T790M EGFR over Wild Type Using Molecular Dynamics and Binding Free Energy Calculations 259
Identification of 4-aryl-1H-pyrrole[2,3-b]pyridine derivatives for the development of new B-Raf inhibitors 258
Exploration and Comparison of the Geometrical and Physicochemical Properties of an αc Allosteric Pocket in the Structural Kinome 258
Histone deacetylases: Structural determinants of inhibitor selectivity 255
Structure of Plasmodium vivax dihydrofolate reductase determined by homology modeling and molecular dynamics refinement 253
Nitrophenyl derivatives as Aldose Reductase inhibitors 252
Enrichment Factor Analyses on G-Protein Coupled Receptors with Known Crystal Structure 252
Physico-chemical properties of anthocyanidins. Part 1. Theoretical evaluation of the stability of the neutral and anionic tautomeric forms 250
Design and discovery of plasmepsin inhibitors using an automated workflow on large scale grids 250
Discovery of new inhibitors of aldose reductase from molecular docking and database screening 250
Prediction of activity and selectivity profiles of human Carbonic Anhydrase inhibitors using machine learning classification models 250
Evaluation of Amides, Carbamates, Sulfonamides, and Ureas of 4-Prop-2-ynylidenecycloalkylamine as Potent, Selective, and Bioavailable Negative Allosteric Modulators of Metabotropic Glutamate Receptor 5 248
Discovery of potent pyrrolo-pyrimidine and purine HDAC inhibitors for the treatment of advanced prostate cancer 246
Activité Antilipoperoxydante d'Extraits Polyphenoliques de Ribes Nigrum L. 246
Novel and less explored chemotypes of natural origin for the inhibition of Hsp90 246
Pharmacological approaches to the treatment of diabetic complications 245
Solvent effects on the tautomerism of apigeninidin 244
Design of dual inhibitors of histone deacetylase 6 and heat shock protein 90 244
Relationship between quantum-chemical descriptors of proton dissociation and experimental acidity contants of variously hydroxylated coumarins. Identification of the biologically active species for xanthine oxidase inhibition 243
Ortho-halogen naphthaleins as specific inhibitors of Lactobacillus casei thymidylate synthase. Conformational properties and biological activity 242
Molecular modeling and crystal structure of ERK2-Hypothemycin complexes 241
Quantitative measurement of proton dissociation and tautomeric constants of apigeninidin 241
Three-dimensional quantitative structure-activity relationship analysis of a set of Plasmodium falciparum dihydrofolate reductase inhibitors using a pharmacophore generation approach 240
Structure-based design of 7-carbamate analogs of geldanamycin 238
Computational polypharmacology comes of age 236
Assessing protein kinase selectivity with molecular dynamics and MM-PBSA binding free energy calculations. 233
Interaction of pyrimethamine, cycloguanil, WR99210 and their analogues with Plasmodium falciparum dihydrofolate reductase: Structural basis of antifolate resistance 232
Crystal structure and molecular modeling of 17-DMAG in complex with human Hsp90 228
Targeting the Hsp90 interactome using in silico polypharmacology approaches 228
QSAR analysis in 2,4-diamino-6,7-dimethoxy quinoline derivatives - α1-adrenoceptor antagonists - using the partial least squares (PLS) method and theoretical molecular descriptors 227
Conformational analysis, molecular modeling and quantitative structure-activity relationships studies of 2,4-diamino-6,7-dimethoxy-2-substituted quinazoline α1-adrenergic antagonists 227
Composition, Superoxide Radicals Scavenging and Antilipoperoxidant Activity of some Edible Fruits 226
Insight into the specificity of Thymidylate synthase from molecular dynamics and free-energy perturbation calculations 226
Isoxazolo-[3,4-d]-pyridazin-7-(6H)-one as a potential substrate for new aldose reductase inhibitors 226
Structure-based and in silico design of Hsp90 inhibitors 225
LigAdvisor: A versatile and user-friendly web-platform for drug design 223
MOLECULAR-ORBITAL STUDY OF THE NITROGEN BASICITY OF PRAZOSIN ANALOGS IN RELATION TO THEIR ALPHA-1-ADRENOCEPTOR BINDING-AFFINITY 220
Second Joint Italian-Swiss Meeting on Medicinal Chemistry , Italy, Modena 19-20 February 2005. 220
Synthesis and aldose reductase inhibitory activity of a new series of benzo[h]cinnolinone derivatives 219
Totale 28.989
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Categoria #
all - tutte 147.007
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 147.007
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021478 0 0 0 0 0 0 0 0 0 0 249 229
2021/20223.063 184 329 377 164 72 146 209 167 300 257 529 329
2022/20232.985 400 373 215 232 323 437 79 270 408 50 141 57
2023/20241.898 64 122 130 160 432 150 166 314 36 41 80 203
2024/20257.475 258 66 122 508 1.314 969 369 633 697 822 799 918
2025/202611.864 823 679 1.233 1.505 1.544 1.196 1.439 649 1.282 1.313 201 0
Totale 40.368