RASTELLI, Giulio
 Distribuzione geografica
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Continente #
NA - Nord America 20.930
AS - Asia 9.692
EU - Europa 8.889
SA - Sud America 1.490
Continente sconosciuto - Info sul continente non disponibili 339
AF - Africa 219
OC - Oceania 52
Totale 41.611
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Nazione #
US - Stati Uniti d'America 20.565
SG - Singapore 2.990
CN - Cina 2.563
GB - Regno Unito 2.559
IT - Italia 1.677
BR - Brasile 1.154
HK - Hong Kong 1.152
VN - Vietnam 1.098
SE - Svezia 973
DE - Germania 932
FI - Finlandia 504
BD - Bangladesh 433
RU - Federazione Russa 421
UA - Ucraina 386
PL - Polonia 365
FR - Francia 293
TR - Turchia 265
KR - Corea 259
IN - India 228
CA - Canada 172
ID - Indonesia 171
BG - Bulgaria 163
NL - Olanda 146
AR - Argentina 120
MX - Messico 101
ES - Italia 96
JP - Giappone 78
IQ - Iraq 70
BE - Belgio 67
IE - Irlanda 59
ZA - Sudafrica 54
PK - Pakistan 52
AU - Australia 48
EC - Ecuador 48
LT - Lituania 48
CO - Colombia 45
AE - Emirati Arabi Uniti 41
AT - Austria 39
VE - Venezuela 37
CL - Cile 34
UZ - Uzbekistan 34
MA - Marocco 33
EG - Egitto 28
SA - Arabia Saudita 27
IR - Iran 25
PH - Filippine 24
RO - Romania 22
KE - Kenya 21
CH - Svizzera 20
JO - Giordania 20
MY - Malesia 19
TN - Tunisia 17
UY - Uruguay 17
AZ - Azerbaigian 16
DO - Repubblica Dominicana 15
PY - Paraguay 15
TH - Thailandia 14
DZ - Algeria 13
KZ - Kazakistan 13
NP - Nepal 13
IL - Israele 12
PT - Portogallo 12
CR - Costa Rica 11
HU - Ungheria 11
PR - Porto Rico 11
AL - Albania 10
GT - Guatemala 10
HN - Honduras 10
RS - Serbia 10
BY - Bielorussia 9
CI - Costa d'Avorio 9
HR - Croazia 9
NG - Nigeria 9
NO - Norvegia 9
PE - Perù 9
SK - Slovacchia (Repubblica Slovacca) 9
TW - Taiwan 9
BO - Bolivia 8
GR - Grecia 8
KH - Cambogia 8
LK - Sri Lanka 8
OM - Oman 8
SN - Senegal 8
CZ - Repubblica Ceca 7
ET - Etiopia 7
EU - Europa 7
JM - Giamaica 7
TT - Trinidad e Tobago 7
AO - Angola 6
LB - Libano 6
NI - Nicaragua 6
PA - Panama 6
BH - Bahrain 5
CY - Cipro 5
QA - Qatar 5
DK - Danimarca 4
SI - Slovenia 4
BA - Bosnia-Erzegovina 3
BB - Barbados 3
GE - Georgia 3
Totale 41.220
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Città #
Fairfield 2.304
Ashburn 2.073
Santa Clara 1.912
Southend 1.675
Singapore 1.598
Woodbridge 1.292
Hong Kong 1.122
Houston 1.023
Chandler 996
Seattle 914
Hefei 865
Cambridge 800
Wilmington 740
Jacksonville 734
San Jose 644
Ann Arbor 602
Nyköping 567
Dearborn 557
London 485
Council Bluffs 465
Beijing 459
Helsinki 359
Ho Chi Minh City 350
Warsaw 349
Los Angeles 286
Hanoi 265
Modena 254
Seoul 238
The Dalles 221
Chicago 207
Milan 207
New York 201
San Diego 190
Dallas 182
Princeton 164
Sofia 155
Munich 143
Eugene 132
Lauterbourg 121
Berlin 118
Izmir 115
Jakarta 114
Des Moines 102
Bologna 101
Buffalo 94
Shanghai 94
São Paulo 94
Frankfurt am Main 85
Salt Lake City 84
Moscow 78
Orem 71
Rome 62
Tokyo 62
Brussels 58
Dublin 54
Boardman 48
Mexico City 47
Phoenix 47
Porto Alegre 44
Toronto 44
Columbus 42
Da Nang 42
Amsterdam 40
Chennai 40
Guangzhou 40
Haiphong 40
Reggio Emilia 40
Tampa 40
Redwood City 39
Atlanta 38
Bremen 38
Elk Grove Village 37
Kent 35
Falls Church 34
Rio de Janeiro 33
Groningen 32
Denver 30
Miano 30
Parma 29
Tashkent 29
Baghdad 27
Nuremberg 27
Biên Hòa 26
Brooklyn 26
Naples 26
Norwalk 26
Paris 26
Johannesburg 25
Montreal 25
San Francisco 24
Belo Horizonte 23
Boston 22
Canberra 22
Hải Dương 22
Nanjing 22
Redondo Beach 22
Yalova 22
Barcelona 21
Mumbai 21
Poplar 21
Totale 28.671
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Nome #
The 1,2,3-triazole ring as a bioisostere in medicinal chemistry 1.312
1-Benzopyran-4-one antioxidants as aldose reductase inhibitors 479
Polypharmacology: challenges and opportunities in drug discovery 442
7-Hydroxy-2-substituted-4-H-1-benzopyran-4-one derivatives as aldose reductase inhibitors: a SAR study 433
Structural models and binding site prediction of the C-terminal domain of human Hsp90: a new target for anticancer drugs 430
BEAR, a Molecular Docking Refinement and Rescoring Method 382
Analytical and Simulation-Based Models for Drug Release and Gel-Degradation in a Tetra-PEG Hydrogel Drug-Delivery System 377
Synthesis and biological activities of novel 17-aminogeldanamycin derivatives 376
An unexpected reversal in the pharmacological stereoselectivity of benzothiadiazine AMPA positive allosteric modulators 376
A rational approach to the design of flavones as xanthine oxidase inhibitors 371
Aldose reductase does catalyse the reduction of glyceraldehyde through a stoichiometric oxidation of NADPH. 361
Application of a post-docking procedure based on MM-PBSA and MM-GBSA on single and multiple protein conformations 355
Fruits of ribes, rubus, vaccinium and prunus genus. Metal contents and genome 348
Discovery of Multitarget Antivirals Acting on Both the Dengue Virus NS5-NS3 Interaction and the Host Src/Fyn Kinases 341
Role of bifidobacteria in the hydrolysis of chlorogenic acid 338
A model of the interaction of substrates and inhibitors with xanthine oxidase 337
A computational workflow for the design of irreversible inhibitors of protein kinases 333
New aldose reductase inhibitors as potential agents for the prevention of long-term diabetic complications 332
Conformational analysis of phthalein derivatives acting as thymidylate synthase inhibitors by means of 1H NMR and quantum chemical calculations 330
Structure-Based Design of Potent Aromatase Inhibitors by High-Throughput Docking 330
Synthesis, activity, and molecular modeling of a new series of tricyclic pyridazinones as selective aldose reductase inhibitors 327
Activity prediction and structural insights of Extracellular Signal-Regulated Kinase 2 inhibitors with molecular dynamics simulations 327
Activity of polyphenolic crude extracts as scavengers of superoxide radicals and inhibitors of xanthine oxidase 324
Advances and applications of binding affinity prediction methods in drug discovery 324
On the integration of in silico drug design methods for drug repurposing 320
BEAR, a novel virtual screening methodology for drug discovery 315
Binding of 1-benzopyran-4-one derivatives to aldose reductase: A free energy perturbation study 315
WISDOM-II: Screening against multiple targets implicated in malaria using computational grid infrastructures 314
Molecular docking: Shifting paradigms in drug discovery 313
1H-NMR conformational studies of some phtalein derivatives acting as thymidylate synthase inhibitors 310
Grid-enabled high throughput virtual screening 310
Molecular dynamics simulations and classical multidimensional scaling unveil new metastable states in the conformational landscape of CDK2 310
Antifungal Activity and DNA Topoisomerase Inhibition of Hydrolysable Tannins from Punica granatum L. 310
Selection of protein conformations for structure-based polypharmacology studies 309
Investigation of the effect of different linker chemotypes on the inhibition of histone deacetylases (HDACs) 309
Theoretical analysis of the addition of hydroxylamine to uracil and 5-fluorouracil as a model for the Thymidylate synthase reaction 305
Valutazione tossicologica di due nuovi inibitori della DHFR del P. falciparum e del P. vivax 303
Structure-based design of an inhibitor modeled at the substrate active site of aldose reductase 299
Binding estimation after refinement, a new automated procedure for the refinement and rescoring of docked ligands in virtual screening 293
Fast and accurate predictions of relative binding free energies using MM-PBSA and MM-GBSA 291
Identification of small-molecule EGFR allosteric inhibitors by high-Throughput docking 288
Drug Repurposing and Polypharmacology to Fight SARS-CoV-2 Through Inhibition of the Main Protease 288
Virtual screening on large scale grids 287
Validation of an automated procedure for the prediction of relative free energies of binding on a set of aldose reductase inhibitors 287
Identification of Target Associations for Polypharmacology from Analysis of Crystallographic Ligands of the Protein Data Bank 286
Mutational analysis of Plasmodium falciparum dihydrofolate reductase: the role of aspartate 54 and phenylalanine 223 on catalytic activity and antifolate binding 283
Fruit of ribes, rubus, vaccinium and prunus genus, metals content and genome 283
A series of diarylsubstituted oximes as potential substrates for new aldose reductase inhibitors 283
Insights into the interaction of negative allosteric modulators with the metabotropic glutamate receptor 5: Discovery and computational modeling of a new series of ligands with nanomolar affinity 283
Heat shock protein 90 and serine/threonine kinase B-Raf inhibitors have overlapping chemical space 282
Structural bases for the inhibition of aldose reductase by phenolic compounds 281
Diabetes complications and their potential prevention: Aldose reductase inhibition and other approaches 281
αC helix displacement as a general approach for allosteric modulation of protein kinases 274
Exploring the binding site of C-terminal Hsp90 inhibitors 274
Structure-based discovery of the first allosteric inhibitors of cyclin-dependent kinase 2 273
Nitrophenyl derivatives as Aldose Reductase inhibitors 272
Identification of 4-aryl-1H-pyrrole[2,3-b]pyridine derivatives for the development of new B-Raf inhibitors 272
Structure–Activity Relationships of Hexahydrocyclopenta[c]quinoline Derivatives as Allosteric Inhibitors of CDK2 and EGFR 272
Computational polypharmacology analysis of the heat shock protein 90 interactome 270
In vitro effects of Plasmodium falciparum dihydrofolate reductase inhibitors on normal and cancer cell proliferation 269
Exploration and Comparison of the Geometrical and Physicochemical Properties of an αc Allosteric Pocket in the Structural Kinome 269
Structure of Plasmodium vivax dihydrofolate reductase determined by homology modeling and molecular dynamics refinement 268
Investigating the Selectivity of Allosteric Inhibitors for Mutant T790M EGFR over Wild Type Using Molecular Dynamics and Binding Free Energy Calculations 268
Prediction of activity and selectivity profiles of human Carbonic Anhydrase inhibitors using machine learning classification models 267
Preparation of thieno[3,2-h]cinnolinones as matrix metalloproteinase inhibitors 266
Pharmacological approaches to the treatment of diabetic complications 263
Enrichment Factor Analyses on G-Protein Coupled Receptors with Known Crystal Structure 263
Promiscuity of inhibitors of human protein kinases at varying data confidence levels and test frequencies 263
Histone deacetylases: Structural determinants of inhibitor selectivity 262
ANTHOCYANIDINES AS INHIBITORS OF XANTHINE-OXIDASE 261
Discovery of new inhibitors of aldose reductase from molecular docking and database screening 260
Design and discovery of plasmepsin inhibitors using an automated workflow on large scale grids 259
Evaluation of Amides, Carbamates, Sulfonamides, and Ureas of 4-Prop-2-ynylidenecycloalkylamine as Potent, Selective, and Bioavailable Negative Allosteric Modulators of Metabotropic Glutamate Receptor 5 259
Physico-chemical properties of anthocyanidins. Part 1. Theoretical evaluation of the stability of the neutral and anionic tautomeric forms 256
Oxidative modification of aldose reductase induced by copper ion. Factors and conditions affecting the process 255
Quantitative measurement of proton dissociation and tautomeric constants of apigeninidin 253
Structure-based design of 7-carbamate analogs of geldanamycin 253
Conformational analysis, molecular modeling and quantitative structure-activity relationships studies of 2,4-diamino-6,7-dimethoxy-2-substituted quinazoline α1-adrenergic antagonists 253
Novel and less explored chemotypes of natural origin for the inhibition of Hsp90 252
Relationship between quantum-chemical descriptors of proton dissociation and experimental acidity contants of variously hydroxylated coumarins. Identification of the biologically active species for xanthine oxidase inhibition 251
Design of dual inhibitors of histone deacetylase 6 and heat shock protein 90 251
Discovery of potent pyrrolo-pyrimidine and purine HDAC inhibitors for the treatment of advanced prostate cancer 250
Molecular modeling and crystal structure of ERK2-Hypothemycin complexes 250
Solvent effects on the tautomerism of apigeninidin 248
Activité Antilipoperoxydante d'Extraits Polyphenoliques de Ribes Nigrum L. 248
Ortho-halogen naphthaleins as specific inhibitors of Lactobacillus casei thymidylate synthase. Conformational properties and biological activity 248
Three-dimensional quantitative structure-activity relationship analysis of a set of Plasmodium falciparum dihydrofolate reductase inhibitors using a pharmacophore generation approach 244
Interaction of pyrimethamine, cycloguanil, WR99210 and their analogues with Plasmodium falciparum dihydrofolate reductase: Structural basis of antifolate resistance 242
Targeting the Hsp90 interactome using in silico polypharmacology approaches 240
Computational polypharmacology comes of age 240
Assessing protein kinase selectivity with molecular dynamics and MM-PBSA binding free energy calculations. 239
Theoretical and experimental study of flavones as inhibitors of xanthine oxidase 239
Insight into the specificity of Thymidylate synthase from molecular dynamics and free-energy perturbation calculations 236
Crystal structure and molecular modeling of 17-DMAG in complex with human Hsp90 235
QSAR analysis in 2,4-diamino-6,7-dimethoxy quinoline derivatives - α1-adrenoceptor antagonists - using the partial least squares (PLS) method and theoretical molecular descriptors 234
Isoxazolo-[3,4-d]-pyridazin-7-(6H)-one as a potential substrate for new aldose reductase inhibitors 234
Structure-based and in silico design of Hsp90 inhibitors 232
LigAdvisor: A versatile and user-friendly web-platform for drug design 231
Composition, Superoxide Radicals Scavenging and Antilipoperoxidant Activity of some Edible Fruits 230
Second Joint Italian-Swiss Meeting on Medicinal Chemistry , Italy, Modena 19-20 February 2005. 228
Totale 30.199
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Categoria #
all - tutte 156.116
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 156.116
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20223.042 184 323 377 164 72 146 209 167 296 254 527 323
2022/20232.952 396 372 215 229 317 435 79 267 399 48 138 57
2023/20241.863 62 121 126 154 427 144 159 314 36 41 79 200
2024/20257.333 254 66 120 499 1.288 953 367 627 683 800 775 901
2025/202613.021 806 665 1.210 1.486 1.525 1.187 1.385 644 1.268 1.291 917 637
2026/2027439 439 0 0 0 0 0 0 0 0 0 0 0
Totale 41.611