MARVERTI, Gaetano
 Distribuzione geografica
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Continente #
NA - Nord America 14.038
EU - Europa 6.554
AS - Asia 6.406
SA - Sud America 1.025
AF - Africa 126
OC - Oceania 17
Continente sconosciuto - Info sul continente non disponibili 6
Totale 28.172
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Nazione #
US - Stati Uniti d'America 13.837
SG - Singapore 1.969
CN - Cina 1.815
GB - Regno Unito 1.807
IT - Italia 1.314
VN - Vietnam 826
BR - Brasile 789
DE - Germania 761
SE - Svezia 688
HK - Hong Kong 630
FR - Francia 400
RU - Federazione Russa 330
FI - Finlandia 306
PL - Polonia 221
UA - Ucraina 207
KR - Corea 206
IN - India 187
TR - Turchia 142
ID - Indonesia 114
CA - Canada 112
BD - Bangladesh 87
BG - Bulgaria 85
AR - Argentina 81
JP - Giappone 81
IQ - Iraq 72
IE - Irlanda 68
NL - Olanda 63
MX - Messico 61
LT - Lituania 58
BE - Belgio 56
ES - Italia 47
ZA - Sudafrica 45
AE - Emirati Arabi Uniti 38
PK - Pakistan 35
CO - Colombia 34
EC - Ecuador 29
VE - Venezuela 27
CL - Cile 26
CZ - Repubblica Ceca 26
MY - Malesia 23
UZ - Uzbekistan 23
CH - Svizzera 22
AT - Austria 19
KE - Kenya 19
SA - Arabia Saudita 16
PY - Paraguay 15
TW - Taiwan 15
NP - Nepal 14
AU - Australia 13
PH - Filippine 13
EG - Egitto 12
MA - Marocco 11
UY - Uruguay 11
AZ - Azerbaigian 10
IR - Iran 10
JO - Giordania 10
BY - Bielorussia 8
DK - Danimarca 8
GR - Grecia 8
RO - Romania 8
DZ - Algeria 7
ET - Etiopia 7
IL - Israele 7
PE - Perù 7
SY - Repubblica araba siriana 7
BO - Bolivia 6
KZ - Kazakistan 6
LK - Sri Lanka 6
PT - Portogallo 6
TN - Tunisia 6
BH - Bahrain 5
CR - Costa Rica 5
GE - Georgia 5
KG - Kirghizistan 5
LB - Libano 5
NO - Norvegia 5
SK - Slovacchia (Repubblica Slovacca) 5
TT - Trinidad e Tobago 5
AL - Albania 4
DO - Repubblica Dominicana 4
EU - Europa 4
HU - Ungheria 4
NG - Nigeria 4
NZ - Nuova Zelanda 4
OM - Oman 4
PS - Palestinian Territory 4
RS - Serbia 4
TH - Thailandia 4
JM - Giamaica 3
LU - Lussemburgo 3
LV - Lettonia 3
MD - Moldavia 3
QA - Qatar 3
SN - Senegal 3
TZ - Tanzania 3
BA - Bosnia-Erzegovina 2
BB - Barbados 2
CG - Congo 2
EE - Estonia 2
KW - Kuwait 2
Totale 28.144
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Città #
Ashburn 1.387
Fairfield 1.252
Santa Clara 1.207
Southend 1.185
Singapore 1.155
Woodbridge 827
Chandler 796
Hong Kong 613
Hefei 585
Ann Arbor 540
San Jose 520
Seattle 520
Houston 518
Cambridge 436
Wilmington 420
Nyköping 378
Jacksonville 376
Dearborn 359
Chicago 320
Los Angeles 301
Beijing 298
Modena 296
London 266
Ho Chi Minh City 242
Frankfurt am Main 237
New York 226
Helsinki 214
Hanoi 206
Seoul 185
Munich 180
Kraków 169
Council Bluffs 151
The Dalles 131
Salt Lake City 124
San Diego 120
Princeton 89
Jakarta 87
Sofia 84
Bologna 83
Moscow 81
Lauterbourg 80
Eugene 79
Fremont 77
São Paulo 74
Orem 72
Izmir 70
Porto Alegre 70
Milan 64
Dublin 63
Shanghai 63
Tampa 62
Dallas 59
Tokyo 55
Buffalo 54
Boardman 49
Elk Grove Village 47
Brussels 46
Parma 44
Warsaw 43
Redwood City 42
Phoenix 38
Da Nang 36
Atlanta 34
Lancaster 34
Des Moines 33
Guangzhou 32
Chennai 31
Denver 31
Miami 30
Grafing 28
Ottawa 28
Sterling 28
Stockholm 28
Toronto 28
Amsterdam 27
Columbus 26
Haiphong 26
Bremen 25
Montreal 25
Norwalk 24
Rome 24
Reggio Emilia 22
Tashkent 22
Brooklyn 21
Kent 21
Manchester 21
Verona 21
Baghdad 20
Dulles 20
Falls Church 20
Mexico City 20
Turku 20
Belo Horizonte 19
Brasília 19
Brno 19
Dong Ket 19
Nairobi 19
Nanjing 19
San Mateo 19
Washington 19
Totale 19.373
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Nome #
Protein–protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase 480
Cisplatin-resistance modulates the effect of protein synthesis inhibitors on spermidine/spermine N-1-acetyltransferase expression 466
N-1,N-12-bis(ethyl)spermine effect on growth of cis-diamminedichloroplatinum(II)-sensitive and -resistant human ovarian-carcinoma cell lines 465
Spermidine/spermine N1-acetyltranferasemodulation by novel folate cycle inhibitors in cisplatin-sensitive and -resistanthuman ovarian cancer cell lines 456
Spermidine/spermine N1-acetyltransferase transient over-expression restores sensitivity of resistant human ovarian cancer cells to N1,N12-bis(ethyl)spermine and to cisplatin 452
Collateral sensitivity to novel thymidylate synthase inhibitors correlates with folate cycle enzymes impairment in cisplatin-resistant human ovarian cancer cells 449
Distamycin A and derivatives as synergic drugs in cisplatin-sensitive and -resistant ovarian cancer cells. 442
Virtual Screening and X-ray Crystallography Identify Non-Substrate Analog Inhibitors of Flavin-Dependent Thymidylate Synthase 423
Optimization of Peptides That Target Human Thymidylate Synthase to Inhibit Ovarian Cancer Cell Growth 422
Synthesis, cytotoxic and combined cDDP activity of new stable curcumin derivatives 408
Cyclic Peptides Acting as Allosteric Inhibitors of Human Thymidylate Synthase and Cancer Cell Growth 400
1H, 13C, 195Pt NMR study on platinum(II) interaction with sulphur containing Amadori compounds 398
Internalization and stability of a thymidylate synthase peptide inhibitor in ovarian cancer cells 395
Newly synthesized curcumin derivatives: crosstalk between chemico-physical properties and biological activity. 389
Studies on the anti-proliferative effects of novel DNA-intercalating bipyridyl-thiourea-Pt(II) complexes against cisplatin-sensitive and -resistant human ovarian cancer cells 385
Polyamine depletion switches the form of 2-deoxy-D-ribose-induced cell death from apoptosis to necrosis in HL-60 cells. 384
Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth 381
Intracellular quantitative detection of human thymidylate synthase engagement with an unconventional inhibitor using tetracysteine-diarsenical-probe technology 379
Repurposing of drugs targeting yap-tead functions 371
Mass Spectrometric/Bioinformatic Identification of a Protein Subset That Characterizes the Cellular Activity of Anticancer Peptides 362
Translational repression of thymidylate synthase by targeting its mRNA 362
Characterization of the cell growth inhibitory effects of a novel DNA-intercalating bipyridyl-thiourea-Pt(II) complex in cisplatin-sensitive and-resistant human ovarian cancer cells 361
Proteomic and bioinformatic studies for the characterization of response to pemetrexed in platinum drug resistant ovarian cancer 361
pH-Promoted Release of a Novel Anti-Tumour Peptide by “Stealth” Liposomes: Effect of Nanocarriers on the Drug Activity in Cis-Platinum Resistant Cancer Cells 360
Inside the biochemical pathways of thymidylate synthase perturbed by anticancer drugs: Novel strategies to overcome cancer chemoresistance 358
Synthesis, chemical and biological studies on new Fe3þ-glycosilated b-diketo complexes for the treatment of iron deficiency 349
The effect of spermine on calcium requirement for protein kinase C association with phospholipid vesicles. 348
Concurrent inhibition of enzymatic activity and NF-Y-mediated transcription of Topoisomerase-IIα by bis-DemethoxyCurcumin in cancer cells 348
A Peptidic Thymidylate-Synthase Inhibitor Loaded on Pegylated Liposomes Enhances the Antitumour Effect of Chemotherapy Drugs in Human Ovarian Cancer Cells 343
Targeting Oxidatively Induced DNA Damage Response in Cancer: Opportunities for Novel Cancer Therapies 342
A proteomic approach to investigate the mechanism of action of anticancer peptides 339
Proteomic Approach to the Detection of the Mechanism of Action of Anticancer Peptides 338
Polyamine depletion protects HL-60 cells from 2-deoxy-D-ribose-induced apoptosis. 328
Differential induction of spermidine/spermine N1-acetyltransferase activity in cisplatin-sensitive and -resistant ovarian cancer cells in response to N1,N12-bis (ethyl)spermine involves transcriptional and post-transcriptional regulation. 323
ANTICANCER DRUGS 320
Effect of Spermine on Membrane-Associated and Membrane-Inserted Forms of Protein Kinase C 316
Modulation of the expression of folate cycle enzymes and polyamine metabolism by berberine in cisplatin-sensitive and -resistant human ovarian cancer cells 315
Modulation of cis-diamminedichloroplatinum(II) accumulation and cytotoxicity by spermine in sensitive and resistant human ovarian carcinoma cells. 314
PTEROATE-PEPTIDE BIOCONJUGATE TARGETING THE FOLATE RECEPTOR IN HUMAN OVARIAN CANCER CELL LINES: TRANSPORT AND MECHANISM OF ACTION. 314
Folic Acid-Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting 304
The 1,10-phenanthroline ligand enhances the antiproliferative activity of dna-intercalating thiourea-pd(Ii) and-pt(ii) complexes against cisplatin-sensitive and-resistant human ovarian cancer cell lines 298
Depletion of Trichoplein (TpMs) Causes Chromosome Mis-Segregation, DNA Damage and Chromosome Instability in Cancer Cells 294
2-Deoxy-D-ribose-induced apoptosis in HL-60 cells is associated with the cell cycle progression by spermidine 293
Spermine protects protein kinase C from phospholipid-induced inactivation 292
Peptides binding to the dimer interface of thymidylate synthase for the treatment of cancer-US8916679 “B2 - Granted patent as second publication”. 290
Human Thymidylate Synthase Inhibitors Halting Ovarian Cancer Growth 290
Chairperson EUTROC- Mayo Conference-Berlin - Preliminary characterization of pharmacodynamic biomarkers for LR-peptide growth inhibition of ovarian cancer (OC) cell models. 282
Designing selective Cys-ligands to unpair the binding of the Human Transcription Enhancer Associated Domain 4 (hTEAD-4) with its modulators to halt cancer cell growth 278
Heat shock protein 90 and serine/threonine kinase B-Raf inhibitors have overlapping chemical space 276
Ligand-Based Virtual Screening and ADME-Tox Guided Approach to Identify Triazolo-quinoxalines as Folate Cycle Inhibitors. 276
Invited lecture to 18th World Congress on Advances in Oncology and 16th International Symposium on Molecular Medicine 10-12 October, 2013, Creta Maris, Hersonissos, Crete, Greece 275
Collateral sensitivity to novel folate cycle inhibitors enhances cisplatin effectiveness against human ovarian cancer cells. 274
Inhibitor of Ovarian Cancer Cells growth by Virtual Screening: A New Thiazole Derivative Targeting Human Thymidylate Synthase 273
Erratum: Protein-protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase (Proceedings of the National Academy of Sciences of the United States of America (2011) 108, 34 (E542-E549) DOI: 10.1073/pnas.1104829108) 272
Effect of spermine on association of protein kinase C with phospholipid vesicles. 270
Relationship Between Spermine and Calcium on the Activation Process of Protein Kinase C. 261
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth 260
N-(naphthyl)-N′-(methoxy carbonyl)thiocarbamide and its Cu(I) complex: synthesis, spectroscopic, X-ray, DFT andin vitrocytotoxicity study 259
Transcriptional activation and cell cycle block are the keys for 5-fluorouracil induced up-regulation of human thymidylate synthase expression 253
Synthesis, molecular structure exploration and in vitro cytotoxicity screening of five novel N, N′- disubstituted thiocarbamide derivatives 252
Development of new metal-chelating multi target drus derived from Curcumin 251
Peptides binding to the dimer interface of thymidylate synthase for the treatment of cancer 247
Folate Receptor Expression and Folate Receptor Targeted Chemotherapy in Cisplatin-sensitive and – resistant Human cancer cell lines Marverti G.a, Pirondi S.a, MarracciniC.a, Frassineti C.a, Helleman J.b, Berns E.M.J.J. b, and Costi, M.P. cThe 4th International Symposium on Folate Receptors and Transporters Cozumel, Mexico October 7 - 11, 2012 239
Copper (I) complexes based on novel N, N'-disubstituted thiocarbamides: Synthesis, spectroscopic, in vitro cytotoxicity, DNA damage and G0/G1 cell cycle arrest studies 238
design, synthesis and biological evaluation of novel YAP:TEAD complex disruptors for thetreatment of colorectal cancer 234
A toolbox of biophysical and analytical assays helps to confirm the activity of novel hTS dimer disrupters (Ddis) with anticancer properties 232
Exploring the biological activity of a library of 1,2,5-Oxadiazole derivatives endowed with antiproliferative activity 231
Glucosyl curcuminoid derivatives: Fe(III) and Ga(III) chelating agents with anti-cancer properties 228
Development of a novel class of YAP:TEAD interface-3 molecular disruptors to treat colorectal carcinoma 227
Serum Mass Spectrometry Proteomics and Protein Set Identification in Response to FOLFOX-4 in Drug-Resistant Ovarian Carcinoma 223
Monodentate Coordination of N, N′-Disubstituted Thiocarbamide Ligands: Syntheses, Structural Analyses, In Vitro Cytotoxicity and DNA Damage Studies of Cu(I) Complexes 218
LC-MS serum proteomics reveals a panel of proteins prognostic of positive responsiveness to bevacizumab therapy in late-stages ovarian cancer patients 213
Stimulation of cis-diamminedichloroplatinum(II) accumulation by modulation of passive permeability with genistein: an altered responce in accumulation-defective resistant cells. 207
Copper (I) complexes of N-(2/4 methoxy/2-chloro-4-nitro) phenyl-N’ (methoxycarbonyl) thiocarbamides as potential anticancer agents: Synthesis, crystal structure, in vitro cytotoxicity and DNA damage studies. 207
SSAT modulation by putative regulators of folate cycle enzymes expression in cisplatin-sensitive and –resistant human ovarian cancer cell lines. 206
Glucosyl curcuminoid derivatives: Fe(III) and Ga(III) chelating agents with anti-cancer properties 206
Identification of a Quinone Derivative as a YAP/TEAD Activity Modulator from a Repurposing Library 205
Targeting the dimer-monomer equilibrium of thymidylate synthase, to accelerate protein degradation and cancer cell growth inhibition 197
Lead optimization of human thymidylate synthase dimer disrupters: from computational studies to evaluation of their biological profiles 196
Experimental and theoretical exploration of molecular structure and anticancer properties of two N, N′–disubstituted thiocarbamide derivatives 195
Synthesis, characterization, Hirshfeld surface, cytotoxicity, DNA damage and cell cycle arrest studies of N, N-diphenyl-N'-(biphenyl-4- carbonyl/4-chlorobenzoyl) thiocarbamides 191
Structural bases for the synergistic inhibition of human thymidylate synthase and ovarian cancer cell growth by drug combinations 191
Effect of spermine on irreversible insertion of protein kinase C into phospholipid vesicles. 188
Differential induction of spermidine/spermine N1-acetyltransferase in cisplatin-sensitive and -resistant human breast cancer cells by N1, N12-bis(ethyl)spermine. 187
Lead-optimization process and characterization of the dissociative effect applied to new dimer disrupters of human Thymidylate Synthase 186
Enhanced anticancer effect of thymidylate synthase dimer disrupters by promoting intracellular accumulation 184
Telomere Dysfunction Is Associated with Altered {DNA} Organization in Trichoplein/Tchp/Mitostatin ({TpMs}) Depleted Cells 183
Precision medicine through proteomics studies in drug resistant colorectal cancer 179
Inhibition of cell growth by accumulated spermine is associated with a transient alteration of cell cycle progression 179
Integrating MS proteomics in the Medicinal Chemistry pipeline as powerful tool to overcome drug resistance issues in colorectal cancer 178
Effetto delle poliammine sulla regolazione della proteina cinasi C. 177
Development of a sensitive biochemical tool to assess the expression levels of recombinant ectopic proteins in in vitro engineered cellular systems 173
Cellular uptake and metabolic degradation of a conjugate of folic acid with an anticancer peptide targeting the human Thymidylate synthase enzyme 171
Synthesis, spectroscopic, crystal structure and in vitro cytotoxicity studies of N-thiophenoyl-N'-substituted phenyl thiocarbamide derivatives 154
Dabrafenib-Panobinostat Salt: Improving Dissolution Rate and Inhibition of BRAF Melanoma Cells 145
MS Proteomics And Biochemical Characterization Of Thymidylate Synthase Dimer Destabilizer E7 To Halt Colorectal Carcinoma 139
Structural, Hirshfeld surface and in vitro cytotoxicity evaluation of five new N-aryl-N’-alkoxycarbonyl thiocarbamide derivatives. 135
Targeting the Interplay of Independent Cellular Pathways and Immunity: A Challenge in Cancer Immunotherapy 123
Synthesis, characterisation, Hirshfeld surface and in vitro cytotoxicity evaluation of new N-aryl-N0-Alkoxycarbonyl thiocarbamide derivatives. 120
Structural insight into YAP-TEAD4 protein-protein interactions as target for cancer treatment 117
Totale 28.268
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Categoria #
all - tutte 104.190
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 104.190
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021835 0 0 0 0 0 0 0 0 0 445 227 163
2021/20221.929 99 121 162 78 100 206 72 90 230 146 402 223
2022/20232.197 239 284 165 235 228 278 82 250 237 32 91 76
2023/20241.790 61 122 119 107 525 202 73 121 31 48 193 188
2024/20254.966 164 49 145 318 923 739 370 319 516 204 566 653
2025/20268.875 671 377 637 1.302 1.944 578 1.191 433 854 888 0 0
Totale 28.426