MARVERTI, Gaetano
 Distribuzione geografica
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Continente #
NA - Nord America 14.771
EU - Europa 6.760
AS - Asia 6.635
SA - Sud America 1.033
Continente sconosciuto - Info sul continente non disponibili 261
AF - Africa 127
OC - Oceania 17
Totale 29.604
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Nazione #
US - Stati Uniti d'America 14.532
SG - Singapore 1.993
CN - Cina 1.827
GB - Regno Unito 1.807
IT - Italia 1.509
VN - Vietnam 827
BR - Brasile 792
DE - Germania 763
SE - Svezia 688
HK - Hong Kong 635
FR - Francia 402
RU - Federazione Russa 330
FI - Finlandia 306
BD - Bangladesh 264
PL - Polonia 221
KR - Corea 207
UA - Ucraina 207
IN - India 187
TR - Turchia 142
CA - Canada 137
ID - Indonesia 116
BG - Bulgaria 85
AR - Argentina 83
JP - Giappone 82
IQ - Iraq 72
IE - Irlanda 68
NL - Olanda 66
MX - Messico 65
LT - Lituania 60
BE - Belgio 57
ES - Italia 48
ZA - Sudafrica 45
AE - Emirati Arabi Uniti 38
CO - Colombia 36
PK - Pakistan 35
EC - Ecuador 30
VE - Venezuela 27
CL - Cile 26
CZ - Repubblica Ceca 26
MY - Malesia 26
UZ - Uzbekistan 23
CH - Svizzera 22
AT - Austria 19
KE - Kenya 19
SA - Arabia Saudita 16
TW - Taiwan 16
PY - Paraguay 15
NP - Nepal 14
AU - Australia 13
PH - Filippine 13
EG - Egitto 12
MA - Marocco 11
UY - Uruguay 11
AZ - Azerbaigian 10
IR - Iran 10
JO - Giordania 10
BY - Bielorussia 8
DK - Danimarca 8
GR - Grecia 8
RO - Romania 8
CR - Costa Rica 7
DZ - Algeria 7
ET - Etiopia 7
IL - Israele 7
PE - Perù 7
SY - Repubblica araba siriana 7
TT - Trinidad e Tobago 7
BO - Bolivia 6
KZ - Kazakistan 6
LK - Sri Lanka 6
PT - Portogallo 6
TN - Tunisia 6
BH - Bahrain 5
GE - Georgia 5
KG - Kirghizistan 5
LB - Libano 5
NO - Norvegia 5
SK - Slovacchia (Repubblica Slovacca) 5
TH - Thailandia 5
AL - Albania 4
DO - Repubblica Dominicana 4
EU - Europa 4
HU - Ungheria 4
JM - Giamaica 4
NG - Nigeria 4
NZ - Nuova Zelanda 4
OM - Oman 4
PS - Palestinian Territory 4
RS - Serbia 4
KW - Kuwait 3
LU - Lussemburgo 3
LV - Lettonia 3
MD - Moldavia 3
PR - Porto Rico 3
QA - Qatar 3
SN - Senegal 3
TZ - Tanzania 3
BA - Bosnia-Erzegovina 2
BB - Barbados 2
CG - Congo 2
Totale 29.317
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Città #
Ashburn 1.519
Fairfield 1.253
Santa Clara 1.244
Southend 1.185
Singapore 1.160
Woodbridge 827
Chandler 796
Hong Kong 617
San Jose 599
Hefei 585
Ann Arbor 540
Seattle 521
Houston 519
Cambridge 438
Wilmington 420
Nyköping 378
Jacksonville 376
Dearborn 359
Chicago 328
Los Angeles 318
Beijing 301
Modena 300
London 266
New York 264
Council Bluffs 243
Ho Chi Minh City 242
Frankfurt am Main 238
Helsinki 214
Hanoi 206
Seoul 186
Munich 180
Kraków 169
The Dalles 131
Salt Lake City 125
San Diego 120
Milan 95
Bologna 89
Princeton 89
Jakarta 87
Sofia 84
Moscow 81
Lauterbourg 80
Eugene 79
Fremont 79
Buffalo 75
São Paulo 74
Orem 73
Porto Alegre 71
Dallas 70
Izmir 70
Shanghai 64
Dublin 63
Tampa 62
Boardman 57
Tokyo 56
Elk Grove Village 47
Brussels 46
Parma 45
Redwood City 43
Warsaw 43
Atlanta 40
Phoenix 39
Da Nang 36
Toronto 36
Lancaster 35
Des Moines 34
Rome 34
Denver 32
Guangzhou 32
Chennai 31
Miami 31
Montreal 29
Columbus 28
Grafing 28
Ottawa 28
Sterling 28
Stockholm 28
Amsterdam 27
Reggio Emilia 27
Haiphong 26
Bremen 25
Norwalk 24
Brooklyn 23
Mexico City 22
Tashkent 22
Verona 22
Kent 21
Manchester 21
Baghdad 20
Dulles 20
Falls Church 20
Turku 20
Washington 20
Belo Horizonte 19
Brasília 19
Brno 19
Dong Ket 19
Nairobi 19
Nanjing 19
San Mateo 19
Totale 19.931
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Nome #
Protein–protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase 490
N-1,N-12-bis(ethyl)spermine effect on growth of cis-diamminedichloroplatinum(II)-sensitive and -resistant human ovarian-carcinoma cell lines 479
Spermidine/spermine N1-acetyltranferasemodulation by novel folate cycle inhibitors in cisplatin-sensitive and -resistanthuman ovarian cancer cell lines 475
Cisplatin-resistance modulates the effect of protein synthesis inhibitors on spermidine/spermine N-1-acetyltransferase expression 469
Optimization of Peptides That Target Human Thymidylate Synthase to Inhibit Ovarian Cancer Cell Growth 464
Collateral sensitivity to novel thymidylate synthase inhibitors correlates with folate cycle enzymes impairment in cisplatin-resistant human ovarian cancer cells 458
Spermidine/spermine N1-acetyltransferase transient over-expression restores sensitivity of resistant human ovarian cancer cells to N1,N12-bis(ethyl)spermine and to cisplatin 456
Distamycin A and derivatives as synergic drugs in cisplatin-sensitive and -resistant ovarian cancer cells. 445
Virtual Screening and X-ray Crystallography Identify Non-Substrate Analog Inhibitors of Flavin-Dependent Thymidylate Synthase 429
Synthesis, cytotoxic and combined cDDP activity of new stable curcumin derivatives 427
1H, 13C, 195Pt NMR study on platinum(II) interaction with sulphur containing Amadori compounds 410
Cyclic Peptides Acting as Allosteric Inhibitors of Human Thymidylate Synthase and Cancer Cell Growth 410
Polyamine depletion switches the form of 2-deoxy-D-ribose-induced cell death from apoptosis to necrosis in HL-60 cells. 405
Newly synthesized curcumin derivatives: crosstalk between chemico-physical properties and biological activity. 403
Internalization and stability of a thymidylate synthase peptide inhibitor in ovarian cancer cells 402
Intracellular quantitative detection of human thymidylate synthase engagement with an unconventional inhibitor using tetracysteine-diarsenical-probe technology 401
Studies on the anti-proliferative effects of novel DNA-intercalating bipyridyl-thiourea-Pt(II) complexes against cisplatin-sensitive and -resistant human ovarian cancer cells 400
Translational repression of thymidylate synthase by targeting its mRNA 400
Repurposing of drugs targeting yap-tead functions 394
Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth 389
Targeting Oxidatively Induced DNA Damage Response in Cancer: Opportunities for Novel Cancer Therapies 383
Concurrent inhibition of enzymatic activity and NF-Y-mediated transcription of Topoisomerase-IIα by bis-DemethoxyCurcumin in cancer cells 379
Characterization of the cell growth inhibitory effects of a novel DNA-intercalating bipyridyl-thiourea-Pt(II) complex in cisplatin-sensitive and-resistant human ovarian cancer cells 378
pH-Promoted Release of a Novel Anti-Tumour Peptide by “Stealth” Liposomes: Effect of Nanocarriers on the Drug Activity in Cis-Platinum Resistant Cancer Cells 375
Inside the biochemical pathways of thymidylate synthase perturbed by anticancer drugs: Novel strategies to overcome cancer chemoresistance 372
Mass Spectrometric/Bioinformatic Identification of a Protein Subset That Characterizes the Cellular Activity of Anticancer Peptides 371
Proteomic and bioinformatic studies for the characterization of response to pemetrexed in platinum drug resistant ovarian cancer 366
Synthesis, chemical and biological studies on new Fe3þ-glycosilated b-diketo complexes for the treatment of iron deficiency 359
The effect of spermine on calcium requirement for protein kinase C association with phospholipid vesicles. 352
A Peptidic Thymidylate-Synthase Inhibitor Loaded on Pegylated Liposomes Enhances the Antitumour Effect of Chemotherapy Drugs in Human Ovarian Cancer Cells 351
A proteomic approach to investigate the mechanism of action of anticancer peptides 343
Proteomic Approach to the Detection of the Mechanism of Action of Anticancer Peptides 342
Polyamine depletion protects HL-60 cells from 2-deoxy-D-ribose-induced apoptosis. 334
Differential induction of spermidine/spermine N1-acetyltransferase activity in cisplatin-sensitive and -resistant ovarian cancer cells in response to N1,N12-bis (ethyl)spermine involves transcriptional and post-transcriptional regulation. 333
Modulation of the expression of folate cycle enzymes and polyamine metabolism by berberine in cisplatin-sensitive and -resistant human ovarian cancer cells 330
ANTICANCER DRUGS 329
Modulation of cis-diamminedichloroplatinum(II) accumulation and cytotoxicity by spermine in sensitive and resistant human ovarian carcinoma cells. 324
Effect of Spermine on Membrane-Associated and Membrane-Inserted Forms of Protein Kinase C 320
PTEROATE-PEPTIDE BIOCONJUGATE TARGETING THE FOLATE RECEPTOR IN HUMAN OVARIAN CANCER CELL LINES: TRANSPORT AND MECHANISM OF ACTION. 319
The 1,10-phenanthroline ligand enhances the antiproliferative activity of dna-intercalating thiourea-pd(Ii) and-pt(ii) complexes against cisplatin-sensitive and-resistant human ovarian cancer cell lines 318
Folic Acid-Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting 313
Depletion of Trichoplein (TpMs) Causes Chromosome Mis-Segregation, DNA Damage and Chromosome Instability in Cancer Cells 311
Human Thymidylate Synthase Inhibitors Halting Ovarian Cancer Growth 310
Peptides binding to the dimer interface of thymidylate synthase for the treatment of cancer-US8916679 “B2 - Granted patent as second publication”. 304
Designing selective Cys-ligands to unpair the binding of the Human Transcription Enhancer Associated Domain 4 (hTEAD-4) with its modulators to halt cancer cell growth 301
Spermine protects protein kinase C from phospholipid-induced inactivation 299
2-Deoxy-D-ribose-induced apoptosis in HL-60 cells is associated with the cell cycle progression by spermidine 299
Effect of spermine on association of protein kinase C with phospholipid vesicles. 295
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth 293
Ligand-Based Virtual Screening and ADME-Tox Guided Approach to Identify Triazolo-quinoxalines as Folate Cycle Inhibitors. 290
Chairperson EUTROC- Mayo Conference-Berlin - Preliminary characterization of pharmacodynamic biomarkers for LR-peptide growth inhibition of ovarian cancer (OC) cell models. 287
Inhibitor of Ovarian Cancer Cells growth by Virtual Screening: A New Thiazole Derivative Targeting Human Thymidylate Synthase 283
Invited lecture to 18th World Congress on Advances in Oncology and 16th International Symposium on Molecular Medicine 10-12 October, 2013, Creta Maris, Hersonissos, Crete, Greece 283
Erratum: Protein-protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase (Proceedings of the National Academy of Sciences of the United States of America (2011) 108, 34 (E542-E549) DOI: 10.1073/pnas.1104829108) 283
Heat shock protein 90 and serine/threonine kinase B-Raf inhibitors have overlapping chemical space 282
Collateral sensitivity to novel folate cycle inhibitors enhances cisplatin effectiveness against human ovarian cancer cells. 278
Relationship Between Spermine and Calcium on the Activation Process of Protein Kinase C. 267
N-(naphthyl)-N′-(methoxy carbonyl)thiocarbamide and its Cu(I) complex: synthesis, spectroscopic, X-ray, DFT andin vitrocytotoxicity study 265
Synthesis, molecular structure exploration and in vitro cytotoxicity screening of five novel N, N′- disubstituted thiocarbamide derivatives 264
Transcriptional activation and cell cycle block are the keys for 5-fluorouracil induced up-regulation of human thymidylate synthase expression 256
Development of new metal-chelating multi target drus derived from Curcumin 256
Peptides binding to the dimer interface of thymidylate synthase for the treatment of cancer 254
Folate Receptor Expression and Folate Receptor Targeted Chemotherapy in Cisplatin-sensitive and – resistant Human cancer cell lines Marverti G.a, Pirondi S.a, MarracciniC.a, Frassineti C.a, Helleman J.b, Berns E.M.J.J. b, and Costi, M.P. cThe 4th International Symposium on Folate Receptors and Transporters Cozumel, Mexico October 7 - 11, 2012 247
Copper (I) complexes based on novel N, N'-disubstituted thiocarbamides: Synthesis, spectroscopic, in vitro cytotoxicity, DNA damage and G0/G1 cell cycle arrest studies 245
Exploring the biological activity of a library of 1,2,5-Oxadiazole derivatives endowed with antiproliferative activity 242
A toolbox of biophysical and analytical assays helps to confirm the activity of novel hTS dimer disrupters (Ddis) with anticancer properties 241
Development of a novel class of YAP:TEAD interface-3 molecular disruptors to treat colorectal carcinoma 240
design, synthesis and biological evaluation of novel YAP:TEAD complex disruptors for thetreatment of colorectal cancer 240
Glucosyl curcuminoid derivatives: Fe(III) and Ga(III) chelating agents with anti-cancer properties 233
Serum Mass Spectrometry Proteomics and Protein Set Identification in Response to FOLFOX-4 in Drug-Resistant Ovarian Carcinoma 232
Monodentate Coordination of N, N′-Disubstituted Thiocarbamide Ligands: Syntheses, Structural Analyses, In Vitro Cytotoxicity and DNA Damage Studies of Cu(I) Complexes 226
LC-MS serum proteomics reveals a panel of proteins prognostic of positive responsiveness to bevacizumab therapy in late-stages ovarian cancer patients 219
Copper (I) complexes of N-(2/4 methoxy/2-chloro-4-nitro) phenyl-N’ (methoxycarbonyl) thiocarbamides as potential anticancer agents: Synthesis, crystal structure, in vitro cytotoxicity and DNA damage studies. 217
Lead optimization of human thymidylate synthase dimer disrupters: from computational studies to evaluation of their biological profiles 214
Identification of a Quinone Derivative as a YAP/TEAD Activity Modulator from a Repurposing Library 212
SSAT modulation by putative regulators of folate cycle enzymes expression in cisplatin-sensitive and –resistant human ovarian cancer cell lines. 211
Glucosyl curcuminoid derivatives: Fe(III) and Ga(III) chelating agents with anti-cancer properties 211
Stimulation of cis-diamminedichloroplatinum(II) accumulation by modulation of passive permeability with genistein: an altered responce in accumulation-defective resistant cells. 210
Enhanced anticancer effect of thymidylate synthase dimer disrupters by promoting intracellular accumulation 207
Experimental and theoretical exploration of molecular structure and anticancer properties of two N, N′–disubstituted thiocarbamide derivatives 207
Targeting the dimer-monomer equilibrium of thymidylate synthase, to accelerate protein degradation and cancer cell growth inhibition 206
Synthesis, characterization, Hirshfeld surface, cytotoxicity, DNA damage and cell cycle arrest studies of N, N-diphenyl-N'-(biphenyl-4- carbonyl/4-chlorobenzoyl) thiocarbamides 202
Lead-optimization process and characterization of the dissociative effect applied to new dimer disrupters of human Thymidylate Synthase 198
Telomere Dysfunction Is Associated with Altered {DNA} Organization in Trichoplein/Tchp/Mitostatin ({TpMs}) Depleted Cells 197
Effect of spermine on irreversible insertion of protein kinase C into phospholipid vesicles. 195
Structural bases for the synergistic inhibition of human thymidylate synthase and ovarian cancer cell growth by drug combinations 195
Differential induction of spermidine/spermine N1-acetyltransferase in cisplatin-sensitive and -resistant human breast cancer cells by N1, N12-bis(ethyl)spermine. 191
Precision medicine through proteomics studies in drug resistant colorectal cancer 188
Development of a sensitive biochemical tool to assess the expression levels of recombinant ectopic proteins in in vitro engineered cellular systems 186
Integrating MS proteomics in the Medicinal Chemistry pipeline as powerful tool to overcome drug resistance issues in colorectal cancer 184
Inhibition of cell growth by accumulated spermine is associated with a transient alteration of cell cycle progression 183
Effetto delle poliammine sulla regolazione della proteina cinasi C. 182
Cellular uptake and metabolic degradation of a conjugate of folic acid with an anticancer peptide targeting the human Thymidylate synthase enzyme 175
Targeting the Interplay of Independent Cellular Pathways and Immunity: A Challenge in Cancer Immunotherapy 171
Synthesis, spectroscopic, crystal structure and in vitro cytotoxicity studies of N-thiophenoyl-N'-substituted phenyl thiocarbamide derivatives 161
Dabrafenib-Panobinostat Salt: Improving Dissolution Rate and Inhibition of BRAF Melanoma Cells 152
MS Proteomics And Biochemical Characterization Of Thymidylate Synthase Dimer Destabilizer E7 To Halt Colorectal Carcinoma 150
Structural, Hirshfeld surface and in vitro cytotoxicity evaluation of five new N-aryl-N’-alkoxycarbonyl thiocarbamide derivatives. 148
Synthesis, characterisation, Hirshfeld surface and in vitro cytotoxicity evaluation of new N-aryl-N0-Alkoxycarbonyl thiocarbamide derivatives. 129
Structural insight into YAP-TEAD4 protein-protein interactions as target for cancer treatment 123
Totale 29.427
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Categoria #
all - tutte 111.257
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 111.257
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.830 0 121 162 78 100 206 72 90 230 146 402 223
2022/20232.197 239 284 165 235 228 278 82 250 237 32 91 76
2023/20241.790 61 122 119 107 525 202 73 121 31 48 193 188
2024/20254.966 164 49 145 318 923 739 370 319 516 204 566 653
2025/20269.781 671 377 637 1.302 1.944 578 1.191 433 854 896 511 387
2026/2027272 252 20 0 0 0 0 0 0 0 0 0 0
Totale 29.604