D'ARCA, Domenico
 Distribuzione geografica
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Continente #
NA - Nord America 8.373
EU - Europa 4.513
AS - Asia 4.440
SA - Sud America 659
AF - Africa 96
OC - Oceania 21
Continente sconosciuto - Info sul continente non disponibili 1
Totale 18.103
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Nazione #
US - Stati Uniti d'America 8.234
SG - Singapore 1.374
CN - Cina 1.314
IT - Italia 1.266
GB - Regno Unito 957
BR - Brasile 514
VN - Vietnam 513
SE - Svezia 482
HK - Hong Kong 448
DE - Germania 435
FR - Francia 267
FI - Finlandia 257
RU - Federazione Russa 214
KR - Corea 154
UA - Ucraina 115
IN - India 114
PL - Polonia 100
ID - Indonesia 95
CA - Canada 82
TR - Turchia 72
ES - Italia 63
NL - Olanda 58
JP - Giappone 57
BD - Bangladesh 55
IE - Irlanda 52
AR - Argentina 51
BG - Bulgaria 49
LT - Lituania 45
IQ - Iraq 43
BE - Belgio 40
MX - Messico 36
PK - Pakistan 29
CH - Svizzera 26
CL - Cile 25
ZA - Sudafrica 25
AT - Austria 20
CO - Colombia 20
EG - Egitto 20
AE - Emirati Arabi Uniti 19
AU - Australia 18
UZ - Uzbekistan 18
SA - Arabia Saudita 17
PH - Filippine 16
MA - Marocco 15
TW - Taiwan 14
VE - Venezuela 14
EC - Ecuador 12
KE - Kenya 11
MY - Malesia 11
CZ - Repubblica Ceca 10
IL - Israele 9
RO - Romania 9
NP - Nepal 8
PY - Paraguay 8
UY - Uruguay 8
DK - Danimarca 7
LB - Libano 7
BY - Bielorussia 6
GR - Grecia 6
JO - Giordania 6
TH - Thailandia 6
AZ - Azerbaigian 5
BH - Bahrain 5
DZ - Algeria 5
IR - Iran 5
KZ - Kazakistan 5
RS - Serbia 5
BO - Bolivia 4
CR - Costa Rica 4
GE - Georgia 4
LK - Sri Lanka 4
NG - Nigeria 4
NO - Norvegia 4
PT - Portogallo 4
TN - Tunisia 4
ET - Etiopia 3
JM - Giamaica 3
NZ - Nuova Zelanda 3
OM - Oman 3
PA - Panama 3
PE - Perù 3
SK - Slovacchia (Repubblica Slovacca) 3
AL - Albania 2
AM - Armenia 2
CG - Congo 2
DO - Repubblica Dominicana 2
EE - Estonia 2
GH - Ghana 2
HU - Ungheria 2
LU - Lussemburgo 2
LV - Lettonia 2
MO - Macao, regione amministrativa speciale della Cina 2
NI - Nicaragua 2
SN - Senegal 2
SV - El Salvador 2
SY - Repubblica araba siriana 2
TT - Trinidad e Tobago 2
BA - Bosnia-Erzegovina 1
BN - Brunei Darussalam 1
EU - Europa 1
Totale 18.092
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Città #
Ashburn 904
Singapore 854
Santa Clara 817
Fairfield 783
Southend 574
Hefei 457
Woodbridge 437
Chandler 435
Hong Kong 433
San Jose 379
Houston 351
Ann Arbor 336
Seattle 303
Cambridge 277
Modena 277
Wilmington 259
Nyköping 254
Beijing 207
Helsinki 201
Jacksonville 191
Dearborn 187
London 182
New York 175
Frankfurt am Main 159
Ho Chi Minh City 156
Los Angeles 149
Seoul 140
Council Bluffs 137
Hanoi 103
Bologna 92
The Dalles 91
Chicago 83
San Diego 83
Jakarta 72
Kraków 69
Munich 68
Lauterbourg 63
Moscow 55
Shanghai 52
Princeton 51
Dublin 50
Fremont 50
São Paulo 49
Milan 48
Sofia 47
Eugene 44
Dallas 40
Porto Alegre 40
Orem 39
Parma 36
Boardman 35
Salt Lake City 34
Izmir 33
Tokyo 31
Brussels 29
Buffalo 29
Warsaw 29
Phoenix 27
Da Nang 26
Denver 24
Toronto 23
Guangzhou 22
Redwood City 22
Bremen 21
Columbus 21
Reggio Emilia 21
Rome 21
Atlanta 20
Kent 20
Montreal 20
Padova 20
Amsterdam 19
Chennai 18
Stockholm 18
Verona 18
Haiphong 17
Tashkent 17
Brooklyn 16
Formigine 16
Poplar 16
Rio de Janeiro 16
Tampa 16
Zurich 16
Boston 15
Cairo 15
Elk Grove Village 15
Paris 15
Piacenza 15
Turku 15
Des Moines 14
Dong Ket 14
Falls Church 14
Madrid 14
Nanjing 14
Washington 14
Biên Hòa 13
Dhaka 13
Lappeenranta 13
Portsmouth 13
Vienna 13
Totale 12.309
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Nome #
Spermidine/spermine N1-acetyltransferase transient over-expression restores sensitivity of resistant human ovarian cancer cells to N1,N12-bis(ethyl)spermine and to cisplatin 453
Optimization of Peptides That Target Human Thymidylate Synthase to Inhibit Ovarian Cancer Cell Growth 423
Cyclic Peptides Acting as Allosteric Inhibitors of Human Thymidylate Synthase and Cancer Cell Growth 404
Enhanced anti-hyperproliferative activity of human thymidylate synthase inhibitor peptide by solid lipid nanoparticle delivery 395
Conveying a newly designed hydrophilic anti-human thymidylate synthase peptide to cisplatin resistant cancer cells: are pH-sensitive liposomes more effective than conventional ones? 388
Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth 382
Intracellular quantitative detection of human thymidylate synthase engagement with an unconventional inhibitor using tetracysteine-diarsenical-probe technology 380
Clusterin decreases oxidative stress in lung fibroblasts exposed to cigarette smoke 379
Repurposing of drugs targeting yap-tead functions 371
ROS, Cell Senescence, and Novel Molecular Mechanisms in Aging and Age-Related Diseases 369
Mass Spectrometric/Bioinformatic Identification of a Protein Subset That Characterizes the Cellular Activity of Anticancer Peptides 363
pH-Promoted Release of a Novel Anti-Tumour Peptide by “Stealth” Liposomes: Effect of Nanocarriers on the Drug Activity in Cis-Platinum Resistant Cancer Cells 363
Proteomic and bioinformatic studies for the characterization of response to pemetrexed in platinum drug resistant ovarian cancer 361
Inside the biochemical pathways of thymidylate synthase perturbed by anticancer drugs: Novel strategies to overcome cancer chemoresistance 359
Ca2+ depletion induces nuclear clusterin, a novel effector of apoptosis in immortalized human prostate cells 358
A Peptidic Thymidylate-Synthase Inhibitor Loaded on Pegylated Liposomes Enhances the Antitumour Effect of Chemotherapy Drugs in Human Ovarian Cancer Cells 344
Targeting Oxidatively Induced DNA Damage Response in Cancer: Opportunities for Novel Cancer Therapies 342
Involvement of epigenetic modification of TERT promoter in response to all-trans retinoic acid in ovarian cancer cell lines 339
ANTICANCER DRUGS 322
PTEROATE-PEPTIDE BIOCONJUGATE TARGETING THE FOLATE RECEPTOR IN HUMAN OVARIAN CANCER CELL LINES: TRANSPORT AND MECHANISM OF ACTION. 315
Folic Acid-Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting 306
Clusterin (SGP-2, ApoJ) expression is downregulated in low- and high-grade human prostate cancer 302
Cell detachment and apoptosis induction of immortalized human prostate epithelial cells are associated with early accumulation of a 45 kDa nuclear isoform of clusterin 301
Huwe1 ubiquitin ligase is essential to synchronize neuronal and glial differentiation in the developing cerebellum 299
The 1,10-phenanthroline ligand enhances the antiproliferative activity of dna-intercalating thiourea-pd(Ii) and-pt(ii) complexes against cisplatin-sensitive and-resistant human ovarian cancer cell lines 298
Depletion of Trichoplein (TpMs) Causes Chromosome Mis-Segregation, DNA Damage and Chromosome Instability in Cancer Cells 294
Mitostatin, a novel mitochondrial protein, that acts as a tumor suppressor in prostate cancer cells 289
The key role of Mitostatin in the maintenance of genome stability 282
Designing selective Cys-ligands to unpair the binding of the Human Transcription Enhancer Associated Domain 4 (hTEAD-4) with its modulators to halt cancer cell growth 282
MITOSTATIN, a putative tumor suppressor on chromosome 12q24.1, is downregulated in human bladder and breast cancer 281
Prevention of urinary bladder cancer in the FHIT knock-out mouse with Rofecoxib, a Cox-2 inhibitor 279
Anticancer activity of green tea polyphenols in prostate gland 278
pH sensitive PEGylated Liposomes delivering active hydrophilic peptide with anticancer activity: in vitro study on cDDP-resistant ovarian cell line 273
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth 263
The chemopreventive action of catechins in the TRAMP mouse model of prostate carcinogenesis is accompanied by clusterin over-expression 256
The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain. 249
MITOSTATIN, A NOVEL MITOCHONDRIAL PROTEIN, THAT ACTS AS A TUMOR SUPPRESSOR IN PROSTATE CANCER CELLS 237
design, synthesis and biological evaluation of novel YAP:TEAD complex disruptors for thetreatment of colorectal cancer 235
A toolbox of biophysical and analytical assays helps to confirm the activity of novel hTS dimer disrupters (Ddis) with anticancer properties 234
Clusterin is down-regulated during the progression of prostate cancer in the tramp mouse model but up-regulated during chemioprevention by green tea catechins administration 234
Nuclear Translocation of a Clusterin Isoform Is Associated with Induction of Anoikis in SV40-Immortalized Human Prostate Epithelial Cells 231
Development of a novel class of YAP:TEAD interface-3 molecular disruptors to treat colorectal carcinoma 230
Serum Mass Spectrometry Proteomics and Protein Set Identification in Response to FOLFOX-4 in Drug-Resistant Ovarian Carcinoma 224
Clusterin gene expression is down-regulated in transformed epithelial cells but up-regulated in fibroblasts from prostate cancer 220
Applying optical tweezers technology to reveal Thymidylate Synthase interactions with its consensus mRNA 218
Mitostatin Is Down-Regulated in Human Prostate Cancer and Suppresses the Invasive Phenotype of Prostate Cancer Cells 217
LC-MS serum proteomics reveals a panel of proteins prognostic of positive responsiveness to bevacizumab therapy in late-stages ovarian cancer patients 214
Prevention of bladder cancer in the FHIT knock-out mouse model with rofecoxib, a COX-2 inhibitor 210
Trichoplein binds PCM1 and controls endothelial cell function by regulating autophagy 207
Identification of a Quinone Derivative as a YAP/TEAD Activity Modulator from a Repurposing Library 205
Targeting the dimer-monomer equilibrium of thymidylate synthase, to accelerate protein degradation and cancer cell growth inhibition 198
Lead optimization of human thymidylate synthase dimer disrupters: from computational studies to evaluation of their biological profiles 197
Structural bases for the synergistic inhibition of human thymidylate synthase and ovarian cancer cell growth by drug combinations 193
Lead-optimization process and characterization of the dissociative effect applied to new dimer disrupters of human Thymidylate Synthase 187
Exploring thymidylate synthase mRNA binding site 1 and human TS protein interaction with optical tweezers and bicistronic expression assay 185
Telomere Dysfunction Is Associated with Altered {DNA} Organization in Trichoplein/Tchp/Mitostatin ({TpMs}) Depleted Cells 184
Enhanced anticancer effect of thymidylate synthase dimer disrupters by promoting intracellular accumulation 184
Bioaccessibility of Flavones, Flavanones, and Flavonols from Vegetable Foods and Beverages 183
Precision medicine through proteomics studies in drug resistant colorectal cancer 182
Integrating MS proteomics in the Medicinal Chemistry pipeline as powerful tool to overcome drug resistance issues in colorectal cancer 182
Exploiting the Optical Tweezer technology to reveal thymidylate synthase interactions with its consensus mRNA 177
Development of a sensitive biochemical tool to assess the expression levels of recombinant ectopic proteins in in vitro engineered cellular systems 174
Cellular uptake and metabolic degradation of a conjugate of folic acid with an anticancer peptide targeting the human Thymidylate synthase enzyme 171
Optical tweezers to investigate at the single-molecule level the interaction of thymidylate synthase with its consensus mRNA 153
Successful prediction of prostate cancer recurrence by gene profiling in combination with clinical data: a 5-year follow-up study. 145
MS Proteomics And Biochemical Characterization Of Thymidylate Synthase Dimer Destabilizer E7 To Halt Colorectal Carcinoma 140
Targeting the Interplay of Independent Cellular Pathways and Immunity: A Challenge in Cancer Immunotherapy 124
Structural insight into YAP-TEAD4 protein-protein interactions as target for cancer treatment 118
Development of a fluorescent anisotropy displacement assay for the optimization of YAP:TEAD molecular disrupters with anticancer activity 86
IDENTIFICATION OF PYRAZOLO-PIPERIDINONE DERIVATIVES TARGETING YAP-TEAD INTERFACE 3 AS ANTICANCER AGENTS THROUGH INTEGRATED VIRTUAL SCREENING AND MASS SPECTROMETRY PROTEOMICS 73
Totale 18.294
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Categoria #
all - tutte 64.488
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 64.488
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021275 0 0 0 0 0 0 0 0 0 0 160 115
2021/20221.185 51 111 71 60 52 106 66 65 129 92 249 133
2022/20231.383 162 172 104 133 150 154 72 135 147 27 67 60
2023/20241.333 56 92 103 75 372 134 65 75 28 40 152 141
2024/20253.532 116 51 109 233 661 498 258 234 356 144 397 475
2025/20265.907 472 285 457 710 956 478 892 320 631 600 106 0
Totale 18.294