TAGLIAZUCCHI, LORENZO
 Distribuzione geografica
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Continente #
AS - Asia 3.088
EU - Europa 2.638
NA - Nord America 2.411
SA - Sud America 317
AF - Africa 49
OC - Oceania 12
Totale 8.515
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Nazione #
US - Stati Uniti d'America 2.347
CN - Cina 1.151
IT - Italia 1.064
SG - Singapore 938
DE - Germania 412
HK - Hong Kong 320
SE - Svezia 272
BR - Brasile 252
GB - Regno Unito 213
VN - Vietnam 161
KR - Corea 156
RU - Federazione Russa 151
ID - Indonesia 94
FI - Finlandia 85
FR - Francia 82
ES - Italia 52
IN - India 52
NL - Olanda 49
JP - Giappone 45
CA - Canada 42
LT - Lituania 36
IE - Irlanda 35
CH - Svizzera 33
PL - Polonia 32
BE - Belgio 28
AR - Argentina 24
ZA - Sudafrica 20
BD - Bangladesh 17
IQ - Iraq 17
MY - Malesia 17
MX - Messico 16
AT - Austria 15
TR - Turchia 15
IR - Iran 14
TW - Taiwan 13
PK - Pakistan 12
UA - Ucraina 12
CZ - Repubblica Ceca 11
SA - Arabia Saudita 11
EC - Ecuador 10
BG - Bulgaria 9
AU - Australia 8
PH - Filippine 8
UZ - Uzbekistan 8
AE - Emirati Arabi Uniti 7
CL - Cile 7
KE - Kenya 7
PY - Paraguay 7
CO - Colombia 6
GR - Grecia 6
LI - Liechtenstein 6
TN - Tunisia 6
DK - Danimarca 5
MA - Marocco 5
MO - Macao, regione amministrativa speciale della Cina 5
NO - Norvegia 5
RO - Romania 5
VE - Venezuela 5
AL - Albania 4
EG - Egitto 4
KZ - Kazakistan 4
NZ - Nuova Zelanda 4
PE - Perù 4
RS - Serbia 4
TH - Thailandia 4
GE - Georgia 3
JM - Giamaica 3
MD - Moldavia 3
NP - Nepal 3
PT - Portogallo 3
AZ - Azerbaigian 2
BH - Bahrain 2
BY - Bielorussia 2
CR - Costa Rica 2
DZ - Algeria 2
ET - Etiopia 2
HU - Ungheria 2
IL - Israele 2
KG - Kirghizistan 2
UY - Uruguay 2
GA - Gabon 1
GH - Ghana 1
GT - Guatemala 1
LA - Repubblica Popolare Democratica del Laos 1
LB - Libano 1
LK - Sri Lanka 1
LV - Lettonia 1
MK - Macedonia 1
OM - Oman 1
PS - Palestinian Territory 1
RE - Reunion 1
Totale 8.515
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Città #
Santa Clara 648
Hefei 613
Singapore 591
Hong Kong 311
Ashburn 300
Modena 177
Frankfurt am Main 162
Seoul 137
Chandler 134
London 130
Nyköping 113
Bologna 97
New York 93
Los Angeles 90
Beijing 88
Jakarta 81
Ho Chi Minh City 66
Munich 61
Milan 57
Reggio Emilia 52
Helsinki 50
Parma 49
Moscow 47
Boardman 43
Shanghai 42
Fairfield 36
Kent 33
Hanoi 32
Chicago 31
The Dalles 31
Dublin 29
Buffalo 28
São Paulo 28
Warsaw 27
Dallas 24
Formigine 24
Houston 24
Seattle 24
Lappeenranta 21
Rome 21
Padova 19
Princeton 18
Amsterdam 17
San Diego 17
Tokyo 17
Turin 17
Nuremberg 16
Orem 16
Piacenza 16
Leuven 15
Phoenix 15
Wilmington 15
Boston 14
Madrid 14
Sassuolo 14
Zurich 14
Chennai 13
Decatur 13
Denver 13
Stockholm 13
Barcelona 12
Düsseldorf 12
Hangzhou 12
Osnabrück 12
Perugia 12
Ravenna 12
Cambridge 11
Ottawa 11
Poplar 11
Portsmouth 11
Rio de Janeiro 11
Brooklyn 10
Brussels 10
Guangzhou 10
Johannesburg 10
Manchester 10
Paris 10
Redondo Beach 10
Salt Lake City 10
Tehran 10
Turku 10
Vienna 10
Washington 10
Woodbridge 10
Atlanta 9
Ferrara 9
Hamburg 9
Lauterbourg 9
San Giovanni Suergiu 9
Brno 8
Charlotte 8
Da Nang 8
Kuala Lumpur 8
Leipzig 8
Mexico City 8
Montreal 8
Naples 8
Sofia 8
Vicenza 8
Ann Arbor 7
Totale 5.340
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Nome #
Folic Acid-Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting 265
Designing selective Cys-ligands to unpair the binding of the Human Transcription Enhancer Associated Domain 4 (hTEAD-4) with its modulators to halt cancer cell growth 241
Exploiting Forster Resonance Energy Transfer (FRET) in the characterization of YAP:TEAD complex disruption 220
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth 214
design, synthesis and biological evaluation of novel YAP:TEAD complex disruptors for thetreatment of colorectal cancer 201
Development of a novel class of YAP:TEAD interface-3 molecular disruptors to treat colorectal carcinoma 191
LC-MS serum proteomics reveals a panel of proteins prognostic of positive responsiveness to bevacizumab therapy in late-stages ovarian cancer patients 190
A toolbox of biophysical and analytical assays helps to confirm the activity of novel hTS dimer disrupters (Ddis) with anticancer properties 189
Serum Mass Spectrometry Proteomics and Protein Set Identification in Response to FOLFOX-4 in Drug-Resistant Ovarian Carcinoma 187
Repurposing the trypanosomatidic gsk kinetobox for the inhibition of parasitic pteridine and dihydrofolate reductases 185
Applying optical tweezers technology to reveal Thymidylate Synthase interactions with its consensus mRNA 181
A dual-Omics approach to identify the modulated proteins/genes in THP-1 cells infected with different drug resistant L. infantum clinical isolates. 177
Current Treatments to Control African Trypanosomiasis and One Health Perspective 177
Structural bases for the synergistic inhibition of human thymidylate synthase and ovarian cancer cell growth by drug combinations 168
Identification of a Quinone Derivative as a YAP/TEAD Activity Modulator from a Repurposing Library 167
Evidence of Pyrimethamine and Cycloguanil Analogues as Dual Inhibitors of Trypanosoma brucei Pteridine Reductase and Dihydrofolate Reductase 165
LC-MS/MS Helps Characterizing THP-1 Cells Proteome After Infection with Drug Resistant Leishmania Strains 163
Coupling a microwave-assisted process with HPLC-ELSD for the extraction, purification and analysis of bioactive policosanols from beeswax 161
Targeting the dimer-monomer equilibrium of thymidylate synthase, to accelerate protein degradation and cancer cell growth inhibition 160
Advances in the set-up of a fluorescence- anisotropy assay for the search of novel inhibitors of the tead-4 complexes 160
Characterization and Valorization of the Agricultural Waste Obtained from Lavandula Steam Distillation for Its Reuse in the Food and Pharmaceutical Fields 157
Lead optimization of human thymidylate synthase dimer disrupters: from computational studies to evaluation of their biological profiles 154
UHPLC-MS/MS screening of the hTEAD surface for the identification of novel allosteric inhibitors with anticancer activity 154
Lead-optimization process and characterization of the dissociative effect applied to new dimer disrupters of human Thymidylate Synthase 153
Enhanced anticancer effect of thymidylate synthase dimer disrupters by promoting intracellular accumulation 148
Integrating MS proteomics in the Medicinal Chemistry pipeline as powerful tool to overcome drug resistance issues in colorectal cancer 147
Exploring thymidylate synthase mRNA binding site 1 and human TS protein interaction with optical tweezers and bicistronic expression assay 146
Leveraging proteomic, bioinformatic and ecotoxicology models to select new targets overcoming L. Infantum drug resistent 143
Precision medicine through proteomics studies in drug resistant colorectal cancer 141
Development of a sensitive biochemical tool to assess the expression levels of recombinant ectopic proteins in in vitro engineered cellular systems 141
Advancing sustainable drug development: comparative preclinical study of H80 and Miltefosine using imaging and proteomics 140
Identification of Innovative Folate Inhibitors Leveraging the Amino Dihydrotriazine Motif from Cycloguanil for Their Potential as Anti-Trypanosoma brucei Agents 139
Cellular uptake and metabolic degradation of a conjugate of folic acid with an anticancer peptide targeting the human Thymidylate synthase enzyme 139
LC-MS/MS proteomics for the rapid and selective screening of drug resistances in Leishmania infantum clinical isolates 138
Exploiting the Optical Tweezer technology to reveal thymidylate synthase interactions with its consensus mRNA 137
Antitarget, Anti-SARS-CoV-2 Leads, Drugs, and the Drug Discovery-Genetics Alliance Perspective 137
EXPLOITING THE OPTICAL TWEEZER, A SINGLE MOLECULE TECHNOLOGY, TO REVEAL THYMIDYLATE SYNTHASE INTERACTIONS WITH ITS CONSENSUS mRNA 136
Expression, purification, and characterization of Transcriptional Enhancer Associated Domain (hTEAD4), a promising target for anticancer agents 136
Label-Free Mass Spectrometry Proteomics Reveals Different Pathways Modulated in THP-1 Cells Infected with Therapeutic Failure and Drug Resistance Leishmania infantum Clinical Isolates 135
Insights into host-target interaction from the proteome modulation analysis through untargeted LC-MS/MS Proteomics of drug resistant L infantum-THP1 infected cells 132
Deciphering Host–Parasite Interplay in Leishmania Infection through a One Health View of Proteomics Studies on Drug Resistance 130
Biochemical characterization of the feedforward loop between CDK1 and FOXM1 in epidermal stem cells 130
The discovery of aryl-2-nitroethyl triamino pyrimidines as anti-Trypanosoma brucei agents 126
Optimization of chemical-biological tools for characterizing the activity of dissociative inhibitor of human thymidylate synthase 125
One Health Approach in Drug Discovery for Leishmaniasis by Targeting Calpain cys-protease. 124
Investigating the mechanism of action of the antiparasitic agent H80 through imaging techniques 119
integrazione della proteomica mediante spettrometria di massa nel processo di Drug Discovery come strumento innovativo per superare la farmacoresistenza 114
Discovery of guanidino-containing benzimidazoles as novel antifolates for Trypanosomiasis 113
Development of guanidino-containing benzimidazoles as novel folate enzymes inhibitors for the treatment of Human African Trypanosomiasis 110
Leveraging proteomics, bioinformatics, and ecotoxicology models to select new targets overcoming L infantum drug resistance. 107
MS Proteomics And Biochemical Characterization Of Thymidylate Synthase Dimer Destabilizer E7 To Halt Colorectal Carcinoma 105
Drug discovery of pyrazolo-piperidinone inhibitors targeting YAP:TEAD interaction and development of a fluorescence anisotropy assay for high-throughput screening 102
Targeting of the Cysteines Surface domain of the Transcriptional Enhancer Associate Domain (TEAD) for anticancer drug discovery 100
Structural insight into YAP-TEAD4 protein-protein interactions as target for cancer treatment 98
Proteomic contribution to the omic path for the identification of novel drugs overcoming resistance in Leishmaniasis. 98
Promoting A Sustainable Medicinal Chemistry Approach With The Cost Action CA21111 - One Health Drugs Against Parasitic Vector Borne Diseases In Europe And Beyond 96
Preclinical investigation of H80 compared to miltefosine: imaging and proteomics for sustainable drug development 82
Development of a fluorescent anisotropy displacement assay for the optimization of YAP:TEAD molecular disrupters with anticancer activity 54
IDENTIFICATION OF PYRAZOLO-PIPERIDINONE DERIVATIVES TARGETING YAP-TEAD INTERFACE 3 AS ANTICANCER AGENTS THROUGH INTEGRATED VIRTUAL SCREENING AND MASS SPECTROMETRY PROTEOMICS 39
Totale 8.587
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Categoria #
all - tutte 35.507
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 35.507
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202154 0 0 0 0 0 0 0 0 3 10 11 30
2021/2022369 26 12 2 2 2 47 18 32 50 41 85 52
2022/2023859 87 69 30 61 76 71 85 99 122 32 73 54
2023/20241.302 62 78 87 73 321 86 84 104 37 40 181 149
2024/20253.270 112 46 129 199 556 465 211 245 329 143 409 426
2025/20262.733 473 319 445 613 638 245 0 0 0 0 0 0
Totale 8.587