P14 | IMMUNE HANDLING OF PET NANOPLASTICS IN POMACEA CANALICULATA: ACCUMULATION BY CIRCULATING AND TISSUE-RESIDENT HEMOCYTES FOLLOWING ACUTE EXPOSURE

The contamination of freshwater ecosystems by nanoplastics (NPs) is a growing concern, yet the eco-immunological responses of freshwater invertebrates remain largely unexplored. We characterized the short-term fate and immunological impact of fluorescently labelled Polyethylene terephthalate (PET)-NPs (Nile Red, mean diameter 82 nm) in the eco-immunological model Pomacea canaliculata, a freshwater snail with remarkable physiological resilience and a well-characterised innate immune system. An...

29 | IL-17 FAMILY IN POMACEA CANALICULATA: FIRST EVIDENCE OF A EXCLUSIVE NEURAL-SPECIFIC MEMBER

Cytokines of the IL-17 family show remarkable evolutionary conservation across metazoan phylogeny, yet their roles at the neuro-immune interface remain largely unexplored in invertebrates. We investigated the IL-17 family in the freshwater gastropod Pomacea canaliculata (Pc), an invertebrate model for comparative neuroimmunobiology, occupying an informative taxonomic position between C. elegans, which possesses IL-17 but lacks immune cells, and mammals, where information on IL-17 neuro-immune...

Bioactive Glasses as Antibacterial Agents: A Review

Bioactive glasses (BGs) have evolved significantly since their discovery in the late 1960s, transitioning from simple biocompatible materials to multifunctional platforms capable of modulating tissue response at the molecular level. BGs can dissolve in physiological environments, precipitate hydroxyapatite, and release therapeutic ions, establishing them as third-generation biomaterials. Among emerging functionalities, antibacterial properties have attracted considerable interest, driven by t...

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